ArticleThe Journal of small animal practice2021
Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors.
Article in The Journal of small animal practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Endocrine diseases in Brazilian small-animal hospitals and referral caseloads: A systematic review and meta-analysis of proportions.Open veterinary journal · 2026Pooled it
- Evaluation of basal cortisol and the adrenocorticotropic hormone stimulation test in 982 dogs undergoing investigation for hypoadrenocorticism.Journal of veterinary internal medicine · 2026Article
- Predicting the likelihood of hypoadrenocorticism in dogs using signalment and routine laboratory results with an ensemble machine learning predictive model.Journal of veterinary internal medicine · 2026Article
- Clinical characteristics, treatment, and outcomes of hypoadrenocorticism in dogs.The Journal of small animal practice · 2025Article
- The impact of age on the Na:K ratio: observations from a general canine population.Frontiers in veterinary science · 2025Article
- Comparison of prednisolone and alternative glucocorticoid dosing protocols for canine hypoadrenocorticism: insights from a survey-based study.Frontiers in veterinary science · 2025Article
- A new future for dog breeding.Animal welfare (South Mimms, England) · 2025Review
- Can we predict hypoadrenocorticism in dogs with resting hypocortisolemia? A predictive model based on clinical, haematological, and biochemical variables.Frontiers in veterinary science · 2024Article
- Text mining for disease surveillance in veterinary clinical data: part one, the language of veterinary clinical records and searching for words.Frontiers in veterinary science · 2024Article
- Phenotypic characterization and quality of life of Labradoodles with idiopathic epilepsy and epilepsy of unknown cause.Frontiers in veterinary science · 2024Article
- Demography, disorders and mortality of pet hamsters under primary veterinary care in the United Kingdom in 2016.The Journal of small animal practice · 2022Article
- How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020).Canine medicine and genetics · 2022Article
- Frequency and risk factors for naturally occurring Cushing's syndrome in dogs attending UK primary-care practices.The Journal of small animal practice · 2022Article
- Evaluation of resting cortisol concentration testing in dogs with chronic gastrointestinal signs.Journal of veterinary internal medicine · 2022Article
- Case Report: Hindlimb Ataxia Concurrent With Seizures by Presumed Osmotic Demyelination Syndrome in a Dog.Frontiers in veterinary science · 2022Article
- Resting cortisol concentrations in dogs presenting to a university teaching hospital with collapse.Journal of veterinary internal medicineArticle
- A retrospective study of hydrocortisone continuous rate infusion compared with administration of dexamethasone boluses in dogs with adrenal crisis.Journal of veterinary internal medicineArticle
- Longitudinal assessment of thyroid function in dogs with hypoadrenocorticism: Clinical outcomes and prevalence of autoantibodies.Journal of veterinary internal medicineArticle
- A case-control survey study of environmental risk factors for primary hypoadrenocorticism in dogs.Journal of veterinary internal medicineArticle
- Prevalence of hypercalcemia in primary hypoadrenocorticism in dogs: Multicenter, retrospective study.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo estimate the frequency, clinical approaches and risk factors of hypoadrenocorticism in dogs under UK primary veterinary care. MATERIALS AND
methodsDogs diagnosed with hypoadrenocorticism were identified from the UK VetCompass™ programme by searching anonymised electronic patient records. Pre-existing and newly diagnosed cases of disease during 2016 were included. Cases were further sub-categorised as having a laboratory-confirmed or presumed diagnosis of hypoadrenocorticism based on the information recorded in the electronic patient records. Descriptive data were manually extracted. Multivariable logistic regression methods were used to identify demographic risk factors.
resultsThere were 177 hypoadrenocorticism cases identified from 905,543 dogs in 2016; 72 laboratory-confirmed and 105 presumed. The 1-year period prevalence for hypoadrenocorticism in all dogs was 0.06% (95% confidence interval: 0.05-0.07%). The most common presenting clinical signs in laboratory-confirmed dogs were lethargy (51/66, 77.3%), anorexia (48/66, 66.7%) and vomiting (48/66, 66.7%). Hyperkalaemia was reported in 47 of 53 (88.7%), hyponatraemia in 46 of 53 (86.8%). Median sodium: potassium ratio was 19.00 (interquartile range: 16.20-20.60). Breed, age, neuter status and insurance status were associated with a laboratory-confirmed diagnosis of hypoadrenocorticism. No sex association with hypoadrenocorticism was observed in the multivariable model. The standard poodle had 51.38 times the odds (95% CI: 14.49-182.18) of hypoadrenocorticism compared with crossbreeds. The labradoodle and West Highland white terrier also had increased odds. CLINICAL SIGNIFICANCE: This is the first epidemiological study to report on hypoadrenocorticism in dogs within the UK primary-care population. These results provide benchmark data of current veterinary activity relating to hypoadrenocorticism in primary-care practices.
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