Evidence map›Paper›PMID 33554708›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Cytokine and chemokine responses to injury and treatment in a nonhuman primate model of hypoxic-ischemic encephalopathy treated with hypothermia and erythropoietin.

Thomas R Wood, Phuong T Vu, Bryan A Comstock, Janessa B Law, Dennis E Mayock, Patrick J Heagerty, Thomas Burbacher, Theo K Bammler, Sandra E Juul

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Peripheral macrophages in the development and progression of structural cerebrovascular pathologies.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Review
  6. Review
  7. Article
  8. RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Thomas R WoodDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
Phuong T VuDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Bryan A ComstockDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Janessa B LawDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
Dennis E MayockDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
Patrick J HeagertyDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Thomas BurbacherDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Theo K BammlerDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Sandra E JuulDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
University of Washington · US

Funding

Mechanisms of Brain Dysmorphology in MN1 C-Terminal Truncation Syndrome, a Novel Intellectual Developmental Disability Disorder P50HD103524 · NICHD · UNIVERSITY OF WASHINGTON · PI Sandra E Juul · 2020 to 2026
$9.9M
Biomarkers of Neonatal Encephalopathy in a Nonhuman Primate ModelR01HD073128 · NICHD · UNIVERSITY OF WASHINGTON · PI JUUL, SANDRA E · 2013 to 2017
$3.2M
NICHD NIH HHS P50 HD103524NICHD NIH HHS R01 HD073128
6 · The paper itself

Abstract

Predicting long-term outcome in infants with hypoxic-ischemic encephalopathy (HIE) remains an ongoing clinical challenge. We investigated plasma biomarkers and their association with 6-month outcomes in a nonhuman primate model of HIE with or without therapeutic hypothermia (TH) and erythropoietin (Epo). Twenty-nine

Indexed as

Hypothermia, InducedAnimalsAnimals, NewbornArea Under CurveBiomarkersChemokinesCytokinesDisease Models, AnimalErythropoietinFemaleHypoxia-Ischemia, BrainIntercellular Signaling Peptides and ProteinsMacaca nemestrinaMonocyte Chemoattractant ProteinsPregnancyROC CurveBiomarkersChemokinesCytokinesErythropoietinIntercellular Signaling Peptides and ProteinsMonocyte Chemoattractant ProteinsAsphyxiaerythropoietinhypothermiahypoxic-ischemic encephalopathyneonatal

Identifiers

PMID33554708
PMCPMC8327104
OpenAlexW3126214286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.