Evidence map›Paper›PMID 33554650›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2021

What do over-trained athletes and patients with neurodegenerative diseases have in common? Mitochondrial dysfunction.

Sergej M Ostojic, Laszlo Ratgeber, Andras Olah, Jozsef Betlehem, Acs Pongras

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sergej M OstojicFaculty of Sport and Physical Education, University of Novi Sad, 21000 Novi Sad, Serbia.ORCID 0000-0002-7270-2541
Laszlo RatgeberFaculty of Health Sciences, University of Pécs, 7622 Pécs, Hungary.
Andras OlahFaculty of Health Sciences, University of Pécs, 7622 Pécs, Hungary.
Jozsef BetlehemFaculty of Health Sciences, University of Pécs, 7622 Pécs, Hungary.
Acs PongrasFaculty of Health Sciences, University of Pécs, 7622 Pécs, Hungary.
University of Pecs · HUUniversity of Novi Sad · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Under pathological conditions and excessive stress, mitochondria may experience a severe and irreversible loss of function. Both strenuous exhaustive exercise and neurodegenerative disorders appear to share defects in mitochondrial function that may fiercely disrupt the integrity and homeostasis of the organelle, leading to perennial pathological substrates. Here, we overview similarities of mitochondrial dysfunction in two conditions and discuss possible areas of interdisciplinary collaboration and research translation between sports medicine and neurology.

Indexed as

AthletesExerciseHumansMitochondriaNeurodegenerative DiseasesReactive Oxygen SpeciesSports MedicineReactive Oxygen SpeciesexerciseMitochondriamitochondrial DNAneurodegenerationreactive oxygen species

Identifiers

PMID33554650
PMCPMC8371304
OpenAlexW3127503779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.