Evidence map›Paper›PMID 33554467›Full record

ArticleZoonoses and public health2021

Human-tick encounters as a measure of tickborne disease risk in lyme disease endemic areas.

Sarah A Hook, Courtney C Nawrocki, James I Meek, Katherine A Feldman, Jennifer L White, Neeta P Connally, Alison F Hinckley

Open access · greenAbstract read
In one paragraph

Article in Zoonoses and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Incidence of Lyme Borreliosis in Europe: A Systematic Review (2005-2020).Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2023
    Pooled it
  2. Trial
  3. Article
  4. Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Tick exposure biomarkers: A One Health approach to new tick surveillance tools.Current research in parasitology & vector-borne diseases · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Does Experimental Reduction of Blacklegged Tick (Pathogens (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Tick species infesting humans in the United States.Ticks and tick-borne diseases · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sarah A HookDivision of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0002-4981-1053
Courtney C NawrockiDivision of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0001-7754-6480
James I MeekYale Emerging Infections Program, New Haven, CT, USA.
Katherine A FeldmanMaryland Department of Health, Baltimore, MD, USA.
Jennifer L WhiteNew York State Department of Health, Albany, NY, USA.ORCID 0000-0001-6343-6109
Neeta P ConnallyWestern Connecticut State University, Danbury, CT, USA.
Alison F HinckleyDivision of Vector-borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.ORCID 0000-0003-2853-5165
Centers for Disease Control and Prevention · USMaryland Department of Health · USNew York State Department of Health · USWestern Connecticut State University · USYale University · US

Funding

Intramural CDC HHS CC999999NCEZID CDC HHS U01CI000307NCEZID CDC HHS U01CI000310NCEZID CDC HHS U01CI000311NCEZID CDC HHS U50 CK000195NCEZID CDC HHS U50CK000195NCEZID CDC HHS U50 CK000199NCEZID CDC HHS U50CK000199NCEZID CDC HHS U50 CK000203NCEZID CDC HHS U50CK000203NCPDCID CDC HHS U01 CI000307NCPDCID CDC HHS U01 CI000310NCPDCID CDC HHS U01 CI000311
6 · The paper itself

Abstract

Entomological measures have long served as proxies for human risk of Lyme disease (LD) and other tickborne diseases (TBDs) in endemic areas of the United States, despite conflicting results regarding the correlation between these measures and human disease outcomes. Using data from a previous TBD intervention study in Connecticut, Maryland and New York, we evaluated whether human-tick encounters can serve as an accurate proxy for risk of TBDs in areas where LD and other Ixodes scapularis-transmitted infections are common. Among 2,590 households consisting of 4,210 individuals, experiencing a tick encounter was associated with an increased risk of both self-reported (RR = 3.17, 95% CI: 2.05, 4.91) and verified TBD (RR = 2.60, 95% CI: 1.39, 4.84) at the household level. Household characteristics associated with experiencing any tick encounter were residence in Connecticut (aOR = 1.86, 95% CI: 1.38, 2.51) or New York (aOR = 1.66, 95% CI: 1.25, 2.22), head of household having a graduate level education (aOR = 1.46, 95% CI: 1.04, 2.08), owning a pet (aOR = 1.80, 95% CI: 1.46, 2.23) and a property size of 2 acres or larger (aOR = 2.30, 95% CI: 1.42, 3.70). Results for individual characteristics were similar to those for households. Future prevention studies in LD endemic areas should consider using human-tick encounters as a robust proxy for TBD risk.

Indexed as

AnimalsArachnid VectorsConnecticutHumansLyme DiseaseMarylandNew YorkRisk FactorsTick BitesTickslyme diseasetickborne diseasetickborne diseasesticks

Identifiers

PMID33554467
PMCPMC10883354
OpenAlexW3127677760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.