Evidence map›Paper›PMID 33554319›Full record

ReviewCurrent urology reports2021

Marijuana, Alcohol, and ED: Correlations with LUTS/BPH.

Granville L Lloyd, Brett Wiesen, Mike Atwell, Anna Malykhina

Open access · greenAbstract readReview
In one paragraph

Review in Current urology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Granville L LloydRocky Mountain Regional Veterans Hospital, Aurora, CO, USA. GRANVILLE.LLOYD@CUANSCHUTZ.EDU.ORCID http://orcid.org/0000-0003-0111-6809
Brett WiesenUniversity of Colorado Anschutz School of Medicine, Aurora, CO, 80045, USA.
Mike AtwellDivision of Urology, Department of Surgery, University of Colorado Anschutz School of Medicine, Aurora, CO, 80045, USA.
Anna MalykhinaDepartment of Surgery, University of Colorado Anschutz School of Medicine, Aurora, CO, 80045, USA.
University of Colorado Anschutz Medical Campus · USRocky Mountain MS Center · US

Funding

Mechanisms of neurogenic bladder dysfunction in a viral murine model of multiple sclerosisR01DK116648 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MALYKHINA, ANNA P · 2020 to 2022
$1.0M
Regulation of pelvic pain and micturition reflex by VEGF in urological chronic pelvic pain syndromeR01DK121506 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MALYKHINA, ANNA P · 2019 to 2021
$700k
NIDDK NIH HHS R01 DK116648NIDDK NIH HHS R01 DK121506
6 · The paper itself

Abstract

purpose of reviewBenign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) is a disease complex with enormous societal burden and yet the pathogenesis of LUTS/BPH is poorly understood. We set out to review the literature on the relationship between depression, marijuana usage, and erectile dysfunction (ED) to LUTS/BPH. RECENT

findingsLUTS/BPH has independent associations with depression as well as with ED. In each case, the causality and mechanistic relationship is unknown. The impact of marijuana, as it increasingly pervades the general population, on the disease complex of LUTS/BPH is not well studied but recent results support short-term benefit and long-term caution. Depression, a form of central nervous dysfunction, and ED, which is likely mediated via endothelial dysfunction, are independently associated with LUTS/BPH. The presence of cannabinoid receptors in urologic organs, coupled with recent population studies, supports a modulatory effect of marijuana on voiding although an enormous knowledge gap remains.

Indexed as

DepressionErectile DysfunctionLower Urinary Tract SymptomsMarijuana SmokingProstatic HyperplasiaAlcohol DrinkingHumansMaleTime FactorsBPHEDLUTSMarijuanaProstateVoiding

Identifiers

PMID33554319
PMCPMC8054558
OpenAlexW3128671027

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.