Evidence map›Paper›PMID 33554254›Full record

ArticleJournal of medical entomology2021

Transmission Potential of Zika Virus by Aedes aegypti (Diptera: Culicidae) and Ae. mediovittatus (Diptera: Culicidae) Populations From Puerto Rico.

Rebecca A Zimler, Donald A Yee, Barry W Alto

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical entomology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Transcriptome analysis ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rebecca A ZimlerFlorida Medical Entomology Laboratory, University of Florida, Vero Beach, FL, USA.
Donald A YeeDepartment of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS, USA.
Barry W AltoFlorida Medical Entomology Laboratory, University of Florida, Vero Beach, FL, USA.ORCID 0000-0001-7054-2081
University of Florida · USUniversity of Southern Mississippi · US

Funding

Meeting Urgent Needs in Surveillance and Diagnostics. ZikaR21AI128188 · NIAID · FIREBIRD BIOMOLECULAR SCIENCES, LLC · PI ALTO, BARRY WILMER, BENNER, STEVEN A · 2017 to 2018
$310k
NIAID NIH HHS R21 AI128188
6 · The paper itself

Abstract

Recurrence of local transmission of Zika virus in Puerto Rico is a major public health risk to the United States, where mosquitoes Aedes aegypti (Linnaeus) and Aedes mediovittatus (Coquillett) are abundant. To determine the extent to which Ae. mediovittatus are capable of transmitting Zika virus and the influence of viremia, we evaluated infection and transmission in Ae. mediovittatus and Ae. aegypti from Puerto Rico using serial dilutions of infectious blood. Higher doses of infectious blood resulted in greater infection rates in both mosquitoes. Aedes aegypti females were up to twice as susceptible to infection than Ae. mediovittatus, indicating a more effective midgut infection barrier in the latter mosquito species. Aedes aegypti exhibited higher disseminated infection (40-95%) than Ae. mediovittatus (<5%), suggesting a substantial midgut escape barrier in Ae. mediovittatus. For Ae. aegypti, transmission rates were low over a range of doses of Zika virus ingested, suggesting substantial salivary gland barriers.

Indexed as

AedesAnimalsHumansMosquito VectorsPuerto RicoSpecies SpecificityZika VirusZika Virus Infectionarbovirusemerging pathogenepidemiologyinvasive and native speciesMosquito

Identifiers

PMID33554254
PMCPMC8122233
OpenAlexW3127760830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.