Evidence map›Paper›PMID 33554139›Full record

ArticleSTAR protocols2021

Regional N-glycan and lipid analysis from tissues using MALDI-mass spectrometry imaging.

Alexandra E Stanback, Lindsey R Conroy, Lyndsay E A Young, Tara R Hawkinson, Kia H Markussen, Harrison A Clarke, Derek B Allison, Ramon C Sun

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Spatial Molecular Imaging of the Glycome Using Mass Spectrometry.Journal of visualized experiments : JoVE · 2025
    Article
  6. Review
  7. Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. The multifaceted roles of the brain glycogen.Journal of neurochemistry · 2024
    Review
  13. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  14. Gys1 Antisense Therapy Prevents Disease-Driving Aggregates and Epileptiform Discharges in a Lafora Disease Mouse Model.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra E StanbackDepartment of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Lindsey R ConroyDepartment of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Lyndsay E A YoungDepartment of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Tara R HawkinsonDepartment of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Kia H MarkussenDepartment of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Harrison A ClarkeDepartment of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.
Derek B AllisonMarkey Cancer Center, Lexington, KY 40536-0298, USA.
Ramon C SunDepartment of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536-0298, USA.

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
Interdisciplinary Research Training in Cancer BiologyT32CA165990 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers, KATHLEEN L. O'CONNOR · 2013 to 2026
$3.2M
Aberrant Glycogen Modulates Cerebral Glucose Metabolism in Aging and Alzheimer's DiseaseR01AG066653 · NIA · UNIVERSITY OF KENTUCKY · PI SUN, RAMON C. · 2020 to 2024
$1.9M
NCI NIH HHS P30 CA177558NCI NIH HHS T32 CA165990NIA NIH HHS R01 AG066653
6 · The paper itself

Abstract

N-glycans and lipids are structural metabolites that play important roles in cellular processes. Both show unique regional distribution in tissues; therefore, spatial analyses of these metabolites are crucial to our understanding of cellular physiology. Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) is an innovative technique that enables

Indexed as

AnimalsDiagnostic ImagingHumansLipidsPolysaccharidesSpatial AnalysisSpecimen HandlingSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationLipidsPolysaccharidesMass spectrometryMetabolism

Identifiers

PMID33554139
PMCPMC7848795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.