Evidence map›Paper›PMID 33554044›Full record

ArticleAnnals of blood2020

Red blood cell alloimmunization and sickle cell disease: a narrative review on antibody induction.

Jeanne E Hendrickson

Open access · diamondAbstract read
In one paragraph

Article in Annals of blood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jeanne E HendricksonDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Mouse Blood Center CoreP01HL132819 · NHLBI · UNIVERSITY OF VIRGINIA · PI LUCKEY, CHANCE MARION JOHN · 2017 to 2021
$12.2M
Responsiveness and non-responsiveness to transfused RBCs in mice and humans.R01HL132951 · NHLBI · YALE UNIVERSITY · PI GALLAGHER, PATRICK G · 2017 to 2020
$1.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS P01 HL132819NHLBI NIH HHS R01 HL132951
6 · The paper itself

Abstract

The high prevalence of red blood cell (RBC) alloantibodies in people with sickle cell disease (SCD) cannot be debated. Why people with SCD are so likely to form RBC alloantibodies, however, remains poorly understood. Over the past decade, a better understanding of non-ABO blood group antigen variants has emerged;

Indexed as

Alloimmunizationinflammationred blood cells (RBC)sickle cell disease (SCD)

Identifiers

PMID33554044
PMCPMC7861514
OpenAlexW3117115871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.