Evidence map›Paper›PMID 33553832›Full record

ReviewJournal of current ophthalmology

An Ophthalmic Insight into Novel Coronavirus 2019 Disease: A Comprehensive Review of the Ocular Manifestations and Clinical Hazards.

Amani E Badawi, Sara S Elsheikh, Sarah Zaher Addeen, Mostafa A Soliman, Rami Abd-Rabu, Walid Shaban Abdella, Elham A Gad

Abstract readReview
In one paragraph

Review in Journal of current ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Concurrent and Post COVID-19 Ophthalmological Implications.Clinical ophthalmology (Auckland, N.Z.) · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amani E BadawiDepartment of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Sara S ElsheikhFaculty of Medicine, Zagazig University, Zagazig, Egypt.
Sarah Zaher AddeenDepartment of Ophthalmology, Al Mouassat University Hospital, Damascus University, Damascus, Syria.
Mostafa A SolimanFaculty of Medicine, Cairo University, Cairo, Egypt.
Rami Abd-RabuEvidence Based Practice Center, Mayo Clinic, Rochester, MN, USA.
Walid Shaban AbdellaFaculty of Medicine, Al Azhar University, Damietta, Egypt.
Elham A GadDepartment of Ophthalmology, Faculty of Medicine, Benha University, Banha, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo discuss the ocular manifestations provoked by novel coronavirus 2019 (COVID-19) disease in humans, the natural history of the disease in the eye, and its treatment.

methodsWe designed a narrative review of the ocular manifestations of COVID-19 based on the literature published till July 30, 2020. The databases were PubMed, Scopus, Cochrane Library, Google Scholar, and ScienceDirect. The inclusion criteria were (1) all types of clinical studies and (2) the topic was COVID-19 and its association to the eye regarding the current guidelines.

resultsFrom 168 abstracts screened, 61 papers fully filled the inclusion criteria after the full-text screening. The 61 records include 13 case reports, 17 prospective (case series or cross-sectional) studies, 8 retrospective studies, 12 literature reviews (one systematic review), and 11 letters to the editor. The majority of the papers agreed that ophthalmic manifestations due to COVID-19 were few and rarely encountered. The main ocular pathology seemed to be conjunctivitis, where the viral polymerase chain reaction also happened to be most detectable. Posterior segment or neuro-ophthalmic manifestations were scarce. Viral genome detection in the eye as well as viral portal of entry to the globe is still vague.

conclusionThe exact incidence of ocular manifestations in COVID-19 disease is uncertain. Conjunctivitis is the most prevalent ocular manifestation. It is still a debate whether the eye is a portal of entry for infection.

Indexed as

ConjunctivitisContact lensNovel coronavirus 2019Ocular transmissionRetinaSevere acute respiratory syndrome coronavirus-2Tear

Identifiers

PMID33553832
PMCPMC7861109

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.