Evidence map›Paper›PMID 33553563›Full record

ArticleOne health (Amsterdam, Netherlands)2021

Retrospective meta-transcriptomic identification of severe dengue in a traveller returning from Africa to Sweden, 1990.

Kristian Alfsnes, Nina Lagerqvist, Sirkka Vene, Jon Bohlin, Jenny Verner-Carlsson, David Ekqvist, Andreas Bråve, Edward C Holmes, Weifeng Shi, John H-O Pettersson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in One health (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Kristian AlfsnesInfectious Disease Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Nina LagerqvistPublic Health Agency of Sweden, Nobels väg 18, SE-171 82 Solna, Sweden.
Sirkka VenePublic Health Agency of Sweden, Nobels väg 18, SE-171 82 Solna, Sweden.
Jon BohlinInfectious Disease Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Jenny Verner-CarlssonPublic Health Agency of Sweden, Nobels väg 18, SE-171 82 Solna, Sweden.
David EkqvistDepartment of Infectious Diseases, University Hospital Linköping, Sweden.
Andreas BråvePublic Health Agency of Sweden, Nobels väg 18, SE-171 82 Solna, Sweden.
Edward C HolmesMarie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences and School of Medical Sciences, the University of Sydney, Sydney, New South Wales 2006, Australia.
Weifeng ShiSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian 271016, China.
John H-O PetterssonPublic Health Agency of Sweden, Nobels väg 18, SE-171 82 Solna, Sweden.
Public Health Agency of Sweden · SENorwegian Institute of Public Health · NOUniversity of Sydney · AULinköping University Hospital · SEShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following retrospective investigation with total RNA-sequencing of samples collected between 7 and 36 days from onset of symptoms we identified dengue virus 3 (DENV-3) and a human pegivirus (HPgV). We conclude that the patient likely suffered from haemorrhagic symptoms due to an atypical severe and undiagnosed dengue infection.

Indexed as

Dengue haemorrhagic feverDengue virusHuman pegivirusMeta-transcriptomicsRNA-sequencingViral haemorrhagic fever

Identifiers

PMID33553563
PMCPMC7851179
OpenAlexW3124357310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.