Evidence map›Paper›PMID 33553470›Full record

ArticleOpen forum infectious diseases2021

Improved Antibiotic Prescribing Practices for Respiratory Infections Through Use of Computerized Order Sets and Educational Sessions in Pediatric Clinics.

Yorgo Zahlanie, Norman S Mang, Kevin Lin, Linda S Hynan, Bonnie C Prokesch

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Impact of institutional treatment guidance on the management and outcomes ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Article
  3. Article
  4. A quasi-experimental analysis comparing antimicrobial usage on COVID-19 and non-COVID-19 wards.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yorgo ZahlanieDivision of Infectious Diseases, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Norman S MangDepartment of Pharmacy, Parkland Health & Hospital System, Dallas, Texas, USA.
Kevin LinDepartment of Pharmacy, Parkland Health & Hospital System, Dallas, Texas, USA.ORCID 0000-0001-7210-2127
Linda S HynanDepartment of Population and Data Sciences (Biostatistics), University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bonnie C ProkeschDivision of Infectious Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-2188-9780
The University of Texas Southwestern Medical Center · USParkland Health & Hospital System · US

Funding

UT Southwestern Center for Translational MedicineUL1TR003163 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2021 to 2025
$39.3M
NCATS NIH HHS UL1 TR003163
6 · The paper itself

Abstract

backgroundComputerized clinical decision support systems (CDSS) have shown promising effectiveness in improving outpatient antibiotic prescribing.

methodsWe developed an intervention in the form of EPIC (Verona, WI, USA) order sets comprised of outpatient treatment pathways for 3 pediatric bacterial acute respiratory infections (ARIs) coupled with educational sessions. Four pediatric clinics were randomized into intervention and control arms over pre- and postimplementation study periods. In the intervention clinics, education was provided in between the 2 study periods and EPIC order sets became available at the beginning of the postimplementation period. The primary end point was the percentage of first-line antibiotic prescribing, and the secondary end points included antibiotic duration and antibiotic prescription modification within 14 days.

resultsA total of 2690 antibiotic prescriptions were included. During the pre-implementation phase, there was no difference in first-line antibiotic prescribing (74.9% vs 77.7%;

conclusionsA computerized CDSS involving treatment pathways in the form of order sets coupled with educational sessions was associated with a higher percentage of first-line antibiotic prescribing and shorter antibiotic duration for the outpatient treatment of pediatric bacterial ARIs.

Indexed as

educationEPICorder setsoutpatientstewardship

Identifiers

PMID33553470
PMCPMC7849952
OpenAlexW3115488143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.