Evidence map›Paper›PMID 33553373›Full record

ArticleAnnals of translational medicine2021

The emergence of various genetic alterations mediated the Osimertinib resistance of a patient harboring heterozygous germline EGFR T790M: a case report.

Bin Liu, Jianwen Qin, Yan Yin, Liang Zhai, Guangxin Liu, Analyn Lizaso, Dongsheng Shi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Novel Co-Occurrence of GermlineInternational journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bin LiuDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Jianwen QinDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Yan YinDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Liang ZhaiDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Guangxin LiuDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Analyn LizasoBurning Rock Biotech, Guangzhou, China.
Dongsheng ShiDepartment of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, China.
Tianjin Chest Hospital · CNBurning Rock Biotech (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (

Indexed as

EGFR T790Mfamilial lung cancergermline T790MOsimertinib resistance

Identifiers

PMID33553373
PMCPMC7859814
OpenAlexW3125104218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.