ArticleAnnals of translational medicine2021
Survey on uric acid in Chinese subjects with essential hypertension (SUCCESS): a nationwide cross-sectional study.
Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Antihypertensive drugs for hyperuricemia in patients with hypertension: a systematic review and network meta-analysis of Chinese trials.BMC cardiovascular disorders · 2025Pooled it
- Effects of Sacubitril/Allisartan versus Olmesartan on serum uric acid in Chinese patients with hypertension and hyperuricaemia.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Trial
- Effects of allisartan-isoproxil-based combination antihypertensive regimen in hypertensive patients with microalbuminuria or hyperuricemia.Journal of clinical hypertension (Greenwich, Conn.) · 2024Trial
- Effect of sacubitril/valsartan on serum uric acid and blood pressure in patients with hypertension and asymptomatic hyperuricemia: A randomized clinical trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Clinical Determinants of Serum Uric Acid Levels in Patients with Obesity and Hypertension.Journal of clinical medicine · 2026Article
- Investigation of the causal effects of hypertension, candesartan, lisinopril, and ramipril on gout.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Uric Acid, Arterial Stiffness and Blood Pressure: A Population-Based Cohort Study.Health science reports · 2026Article
- Systemic immune-inflammation index and uric acid mediate the association between obesity and hypertension in young and middleaged adults.Scientific reports · 2025Article
- Assessment of drug induced hyperuricemia and gout risk using the FDA adverse event reporting system.Scientific reports · 2025Article
- Highlights of the 2024 Chinese hypertension guidelines.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Review
- U-shaped relationship between uric acid levels and all-cause mortality in patients with hypertension.Scientific reports · 2025Article
- Correlation study between serum uric acid level and cognitive impairment in middle-aged and elderly patients with hypertension: based on an explainable predictive model.Frontiers in neurology · 2025Article
- Diagnostic role of SPP1 and collagen IV in a rat model of type 2 diabetes mellitus with MASLD.Scientific reports · 2024Article
- Article
- Development and validation of a prediction model for hyperuricemia risk in hypertensive patients.American journal of cardiovascular disease · 2024Article
- Exploring the Association between Low-dose Aspirin Intake and Hyperuricemia in Individuals over 40: A Cross-Sectional Study using NHANES Data (2011-2018).Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Hyperuricemia is associated with more cardiometabolic risk factors in hypertensive younger Chinese adults than in elderly.Frontiers in cardiovascular medicine · 2023Article
- Hyperuricaemia, gout and related adverse events associated with antihypertensive drugs: A real-world analysis using the FDA adverse event reporting system.Frontiers in pharmacology · 2022Article
- Medical Students' Perspective and Knowledge of Asymptomatic Hyperuricemia and Gout Management: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperuricemia (HUA) is associated with hypertension and increased cardiovascular risk. Current data regarding the prevalence of HUA in Chinese hypertensive patients are lacking. Our study aims to explore the prevalence and determinants of HUA in Chinese hypertensive adults.
methodsTreatment-naive hypertensive adults or those taking single antihypertensive agent were included in a nationwide cross-sectional study. Basic demographics, antihypertensive medications, serum uric acid (UA), and other parameters were documented.
resultsThe overall prevalence rate of HUA was 38.7% among 33,785 valid cases, 35.1% for males (UA >420 µmol/L), and 45.2% for females (UA >360 µmol/L). A multiple logistic regression analysis, adjusted for demographic and clinical factors (model 1), revealed that female sex [odds ratio (OR), 95% CI, 1.43, 1.36-1.51], age of ≥65 years (1.12, 1.05-1.19), low evaluated glomerular filtration rate [eGFR; 2.06, 1.91-2.23, the lowest [Q1]
conclusionsThe prevalence rate of HUA in Chinese hypertensive patients was 38.7%. Female sex, aging (≥65 years), and low eGFR were independent predictors of HUA. HUA was lower among the patients who were taking losartan, valsartan, and nifedipine. Western region residents, new-onset hypertension, longer hypertension duration, aspirin use, higher FBG, TG, LDL-C levels and BMI were potential risk factors for HUA.
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