Evidence map›Paper›PMID 33553259›Full record

ArticleFrontiers in cardiovascular medicine2020

Umbilical Cord Pericytes Provide a Viable Alternative to Mesenchymal Stem Cells for Neonatal Vascular Engineering.

William Cathery, Ashton Faulkner, Eva Jover, Iker Rodriguez-Arabaolaza, Anita C Thomas, Elisa Avolio, Massimo Caputo, Paolo Madeddu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

William CatheryBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Ashton FaulknerBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Eva JoverBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Iker Rodriguez-ArabaolazaBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Anita C ThomasBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Elisa AvolioBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Massimo CaputoBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Paolo MadedduBristol Medical School, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
University of Bristol · GBNavarrabiomed · ES

Funding

British Heart Foundation CH/17/1/32804British Heart Foundation PG/15/33/31394Medical Research Council MR/N027086/1
6 · The paper itself

Abstract

Reconstructive surgery of congenital heart disease (CHD) remains inadequate due to the inability of prosthetic grafts to match the somatic growth of pediatric patients. Functionalization of grafts with mesenchymal stem cells (MSCs) may provide a solution. However, MSCs represent a heterogeneous population characterized by wide diversity across different tissue sources. Here we investigated the suitability of umbilical cord pericytes (UCPs) in neonatal vascular engineering. Explant outgrowth followed by immunomagnetic sorting was used to isolate neural/glial antigen 2 (NG2)

Indexed as

congenital heart diseasepericytesregenerative medicinetissue engineeringvascular grafts

Identifiers

PMID33553259
PMCPMC7859275
OpenAlexW3119976445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.