ReviewFrontiers in cardiovascular medicine2020
Hemodynamic Relevance of Anomalous Coronary Arteries Originating From the Opposite Sinus of Valsalva-In Search of the Evidence.
Review in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 86 citations in OpenAlex.
- Accuracy of CT-derived interarterial and intramural anomalous coronary arteries anatomy compared with 3D-reconstructed IVUS in-vivo reference.The international journal of cardiovascular imaging · 2026Article
- Long intramural left coronary artery confined to the left sinus of Valsalva with diastolic deformation: a case report.European heart journal. Case reports · 2026Article
- Single Coronary Artery in the Context of Vascular Disease: Anatomy, Development, Multimodality Imaging, and Clinical Interpretation.Journal of clinical medicine · 2026Review
- Clinical use of coronary computed tomography angiography-derived fractional flow reserve: expert consensus by an International Working Group.European radiology · 2026Article
- Coronary Artery Anomalies and Anatomical Variants: Cross-Sectional Diagnostic Imaging and Clinical Background.Journal of imaging · 2026Review
- Quantitative and qualitative CT features of coronary artery anomalies with an interarterial course: exploratory associations with exertional symptoms.The international journal of cardiovascular imaging · 2026Article
- Multimodality Approach to Coronary Ischemic Testing in Pediatric Patients: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2026Review
- An 11-Year-Old Athlete With Dynamic Stenosis of Coronary Artery Anomaly With Normal FFR-Dobutamine But Abnormal iFR-Dobutamine.JACC. Case reports · 2026Article
- Coronary artery anomalies in children: subtype classification, age of onset, clinical outcomes, and prognostic implications.BMC pediatrics · 2026Article
- Computed tomography-derived biomechanical simulations as a proof-of-concept tool for evaluating coronary dynamics in anomalous aortic origin of coronary arteries.European heart journal. Digital health · 2026Article
- Case Report: Syncope in an 11-year-old girl induced by anomalous aortic origin of the coronary artery, initially diagnosed via echocardiography.Frontiers in cardiovascular medicine · 2026Article
- [Anomalous origin of the left anterior descending artery from the right coronary artery: A case report].Revista medica del Instituto Mexicano del Seguro Social · 2026Article
- Imaging of common coronary artery anomalies and imaging features important for clinical decision-making.Pediatric radiology · 2025Review
- Primary Angioplasty for STEMI Patients With Anomalous Left Coronary Artery Arising From Right Coronary Sinus.JACC. Case reports · 2025Article
- Adults with anomalous aortic origin of a coronary artery: impact of invasive functional testing on clinical decision making-insights from the MuSCAT registry.European heart journal. Imaging methods and practice · 2025Article
- The Essential Role of Physiologic Assessment in Anomalous Aortic Origin of Coronary Arteries: Moving Beyond Purely Anatomical Evaluation.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Percutaneous coronary intervention in anomalous aortic origin of a coronary artery: a rare case report of a dual-left anterior descending artery with a pre-pulmonary course.European heart journal. Case reports · 2025Article
- Catheterization Techniques for Anomalous Aortic Origin of Coronary Arteries.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Review
- Invasive Diagnostic Procedure in Patient With Anomalous Aortic Origin of a Right Coronary Artery.JACC. Case reports · 2025Article
- Hemodynamic Relevance Evaluation of Coronary Artery Anomaly During Stress Using FFR/IVUS in an Artificial Twin.JACC. Case reports · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary artery anomalies (CAA) represent a heterogeneous group of congenital disorders of the arterial coronary circulation, defined by an anomalous origin of the coronary ostium and/or vessel course. Of particular interest are anomalous coronary arteries originating from the opposite sinus of Valsalva (ACAOS). The interarterial variants (with the anomalous vessel situated between the great arteries) are historically called "malignant," based on an anticipated higher risk for myocardial ischemia and sudden cardiac death (SCD), especially affecting young patients during strenuous physical activity. However, the interarterial course itself may not be the predominant cause of ischemia, but rather represents a surrogate for other ischemia-associated anatomical high-risk features. As the exact pathophysiology of ACAOS is not well-understood, there is a lack of evidence-based guidelines addressing optimal diagnostic work-up, downstream testing, sports counseling, and therapeutic options in patients with ACAOS. Therefore, treating physicians are often left with uncertainty regarding the clinical management of affected patients. This review focuses on the pathophysiologic consequences of ACAOS on myocardial ischemia and discusses the concept of the interplay between fixed and dynamic coronary stenosis. Further, we discuss the advantages and limitations of the different diagnostic modalities and give an outlook by highlighting the gaps of knowledge in the assessment of such anomalies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.