Evidence map›Paper›PMID 33553103›Full record

ReviewFrontiers in chemistry2020

Biomedically Relevant Applications of Bolaamphiphiles and Bolaamphiphile-Containing Materials.

Jake R Hughes, Alyssa S Miller, Camryn E Wallace, Gopi Nath Vemuri, Peter M Iovine

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Multicharged Zwitterions form Superior Antifouling Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Highly Effective Biocides againstACS infectious diseases · 2024
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jake R HughesDepartment of Chemistry and Biochemistry, University of San Diego, San Diego, CA, United States.
Alyssa S MillerDepartment of Chemistry and Biochemistry, University of San Diego, San Diego, CA, United States.
Camryn E WallaceDepartment of Chemistry and Biochemistry, University of San Diego, San Diego, CA, United States.
Gopi Nath VemuriDepartment of Chemistry and Biochemistry, University of San Diego, San Diego, CA, United States.
Peter M IovineDepartment of Chemistry and Biochemistry, University of San Diego, San Diego, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bolaamphiphiles (BAs) are structurally segmented molecules with rich assembly characteristics and diverse physical properties. Interest in BAs as standalone active agents or as constituents of more complex therapeutic formulations has increased substantially in recent years. The preorganized amphiphilicity of BAs allows for a range of biological activities including applications that rely on multivalency. This review summarizes BA-related research in biomedically relevant areas. In particular, we review BA-related literature in four areas: gene delivery, antimicrobial materials, hydrogels, and prodrugs. We also discuss several distinguishing characteristics of BAs that impact their utility as biomedically relevant compounds.

Indexed as

antimicrobialsbiomaterialsbolaamphiphilesbolaform amphiphilegene deliveryprodrugs

Identifiers

PMID33553103
PMCPMC7855593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.