SynthesisFrontiers in oncology2020
Survival and Complications in Pediatric Patients With Cancer and COVID-19: A Meta-Analysis.
Synthesis in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The impact of estrogen status on the gut microbiome: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Evidence linking COVID-19 and the health/well-being of children and adolescents: an umbrella review.BMC medicine · 2024Pooled it
- COVID-19 outcomes in paediatric cancer: A large scale pooled meta-analysis of 984 cancer patients.Reviews in medical virology · 2022Pooled it
- SARS-CoV-2 in pediatric cancer: a systematic review.European journal of pediatrics · 2022Pooled it
- The Global Impact of COVID-19 on Childhood Cancer Outcomes and Care Delivery - A Systematic Review.Frontiers in oncology · 2022Pooled it
- Mortality in children with cancer and SARS-CoV-2 in Latin America: A systematic review.Frontiers in pediatrics · 2022Pooled it
- Risk Factors for Severe Outcomes Among Pediatric Cancer Patients with Respiratory Viral Infection.Microorganisms · 2025Article
- Global, regional, and national burden for childhood and adolescent cancers from 1990 to 2021: from the Global Burden of Disease Study 2021.Pediatric surgery international · 2025Article
- Clinical Outcomes of Pediatric Cancer Patients with COVID-19: A Cross-Sectional Study.International journal of hematology-oncology and stem cell research · 2024Article
- Challenges in Treating Pediatric Cancer Patients during the COVID-19 Pandemic: Balancing Risks and Care.Viruses · 2024Review
- The Characteristics and Follow-Up of SARS-CoV-2 Infection in Pediatric Oncology Patients.Cureus · 2023Article
- Impact of the COVID-19 pandemic on paediatric renal tumour presentation and management, a SIOP renal tumour study group study.Cancer medicine · 2023Article
- SARS-CoV-2 Infection in Children with Idiopathic Nephrotic Syndrome: A Multicentric Study.Indian pediatrics · 2023Article
- The Impact of COVID-19 on Pediatric Malignancy Diagnosis and Treatment: Never the Same but Lessons Learned.Vaccines · 2023Review
- Identification of Comorbidities, Genomic Associations, and Molecular Mechanisms for COVID-19 Using Bioinformatics Approaches.BioMed research international · 2023Article
- Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society.Pediatric blood & cancer · 2022Article
- Manifestations of COVID-19 infection in children with malignancy: A single-center experience in Jordan.World journal of virology · 2022Article
- Prediction and analysis of COVID-19 daily new cases and cumulative cases: times series forecasting and machine learning models.BMC infectious diseases · 2022Article
- Observational
- COVID-19 in Children and Adolescents: Characteristics and Specificities in Immunocompetent and Oncohematological Patients.Mediterranean journal of hematology and infectious diseases · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected all age groups, including the pediatric population, in 3-5% of all cases. We performed a meta-analysis to understand the survival and associated complications in pediatric cancer patients as well as their hospitalization, intensive care, and ventilation care (supplemental oxygen/endotracheal intubation) needs.
methodsA systematic search was performed using MEDLINE, TRIP Database, International Clinical Trials Registry Platform (WHO), The Cochrane Library, Wiley, LILACS, and Google Scholar. Additionally, a search using the snowball method was performed in
resultsThe overall survival was 99.4%. There were no statistically significant differences in the risk of hospitalization between hematological malignancies and solid tumors (95% confidence interval [CI] 0.48-18.3; OR = 2.94). The risk of being admitted to the intensive care unit was also not different between hematological malignancies and other tumors (95% CI 0.35-5.81; OR = 1.42). No differences were found for the need of ventilatory support (95% CI 0.14-3.35; OR = 0.68). Although all the studies were cross-sectional, the mortality of these patients was 0.6% at the time of analysis.
conclusionsIn the analyzed literature, survival in the studied group of patients with COVID-19 was very high. Suffering from hematological neoplasia or other solid tumors and COVID-19 was not a risk factor in children with cancer for the analyzed outcomes.
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