Evidence map›Paper›PMID 33552961›Full record

ArticleFrontiers in oncology2020

Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma.

Rong Liang, Jinyan Zhang, Zhihui Liu, Ziyu Liu, Qian Li, Xiaoling Luo, Yongqiang Li, Jiazhou Ye, Yan Lin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rong LiangDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Jinyan ZhangDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Zhihui LiuDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Ziyu LiuDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Qian LiDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Xiaoling LuoDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, China.
Yongqiang LiDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Jiazhou YeDepartment of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.
Yan LinDepartment of Medical Oncology, Guangxi Medical University Cancer Hospital, Nanning, China.
Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-binding motif protein 8A (RBM8A) is abnormally overexpressed in hepatocellular carcinoma (HCC) and involved in the epithelial-mesenchymal transition (EMT). The EMT plays an important role in the development of drug resistance, suggesting that RBM8A may be involved in the regulation of oxaliplatin (OXA) resistance in HCC. Here we examined the potential involvement of RBM8A and its downstream pathways in OXA resistance using

Indexed as

drug resistancehepatocellular carcinomahistone deacetylase 9molecular networkoxaliplatinRNA-binding motif protein 8A

Identifiers

PMID33552961
PMCPMC7862710
OpenAlexW3121872130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.