Evidence map›Paper›PMID 33552930›Full record

ArticleInternet interventions2021

Internet-delivered Mindfulness-Based Cognitive Therapy for anxiety and depression in cancer survivors: Predictors of treatment response.

Eva Rames Nissen, Robert Zachariae, Maja O'Connor, Viktor Kaldo, Carsten René Jørgensen, Inger Højris, Michael Borre, Mimi Mehlsen

Open access · goldAbstract read
In one paragraph

Article in Internet interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Eva Rames NissenDepartment of Psychology and Behavioral Sciences, Aarhus University, Aarhus, Denmark.
Robert ZachariaeDepartment of Psychology and Behavioral Sciences, Aarhus University, Aarhus, Denmark.
Maja O'ConnorDepartment of Psychology and Behavioral Sciences, Aarhus University, Aarhus, Denmark.
Viktor KaldoCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Sweden.
Carsten René JørgensenDepartment of Psychology and Behavioral Sciences, Aarhus University, Aarhus, Denmark.
Inger HøjrisDepartment of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Michael BorreDepartment of Urology, Aarhus University Hospital, Aarhus, Denmark.
Mimi MehlsenDepartment of Psychology and Behavioral Sciences, Aarhus University, Aarhus, Denmark.
Aarhus University · DKAarhus University Hospital · DKLinnaeus University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study investigates possible predictors of treatment response in an Internet-delivered Mindfulness-Based Cognitive Therapy (iMBCT) intervention with therapist support. This iMBCT program, a fully online delivered intervention with asynchronous therapist support, has previously been shown to be efficacious in reducing symptoms of anxiety and depression in women treated for breast cancer and men treated for prostate cancer.

methodsEighty-two breast- and prostate cancer survivors experiencing psychological distress received 8 weeks of therapist-guided iMBCT. Primary outcomes were improvement in anxiety and depression scores from baseline to post-treatment and from baseline to six-months follow-up. Clinical predictors included levels of depression and anxiety at the time of screening and at baseline, as well as time since diagnosis. Demographic predictors included age and educational level. Therapy-related predictors included working alliance, self-compassion, and five facets of mindfulness. Mixed Linear Models were employed to test the prediction effects over time.

resultsHigher levels of baseline depression were associated with increased treatment response in anxiety at post-treatment, and lower levels of self-compassion were associated with increased treatment response in depression at post-treatment. None of the proposed predictors significantly predicted treatment response at six-months follow-up.

conclusionThe findings suggest that iMBCT can be provided for cancer survivors regardless of their age, educational level, and time since diagnosis (up to five years) and that therapeutic alliance is not crucial for treatment response. We did not identify characteristics predicting treatment response, although many factors were tested. Still, other characteristics may be predictors, and given the relatively small sample size and a large number of statistical tests, the results should be interpreted with caution.

Indexed as

AnxietyBDI-II, Beck Depression Inventory IIBreast cancerDepressionFFMQ-SF-AA, FFMQ-SF subscale Acting with AwarenessFFMQ-SF-DS, FFMQ-SF subscale DescribingFFMQ-SF, Five Facet Mindfulness Questionnaire – Short FormFFMQ-SF-NJ, FFMQ-SF subscale Non-Judging of inner experienceFFMQ-SF-NR, FFMQ-SF subscale Non-Reactivity to inner experienceFFMQ-SF-OB, FFMQ-SF subscale ObservingiMBCT, Internet-delivered Mindfulness-Based Cognitive TherapyiMBI, Internet-delivered Mindfulness-Based InterventionInternet-delivered therapyMBCT, Mindfulness-Based Cognitive TherapyMBI, Mindfulness-Based InterventionMBSR, Mindfulness-Based Stress ReductionMindfulness-Based Cognitive TherapyProstate cancerRCT, randomized controlled trialSCS-SF, Self-Compassion Scale – Short FormSTAI-Y, State-Trait Anxiety Inventory, Y-FormWAI-C, Working Alliance Inventory – Client Form

Identifiers

PMID33552930
PMCPMC7843453
OpenAlexW3119204179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.