Evidence map›Paper›PMID 33552716›Full record

ArticlePeerJ2021

COVID-19 mortality in cancer patients: a report from a tertiary cancer centre in India.

Anurag Mehta, Smreti Vasudevan, Anuj Parkash, Anurag Sharma, Tanu Vashist, Vidya Krishna

Abstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  11. Treatment Delay during Radiotherapy of Cancer Patients due to COVID-19 Pandemic.Asian Pacific journal of cancer prevention : APJCP · 2022
    Article
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  13. Nurses in NICUs' views on nosocomial infection prevention.Journal of education and health promotion · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anurag MehtaDepartment of Laboratory, Transfusion and Molecular Diagnostics Services, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.
Smreti VasudevanDepartment of Research, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.ORCID 0000-0003-3077-0076
Anuj ParkashDepartment of Laboratory and Transfusion Services, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.
Anurag SharmaDepartment of Research, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.
Tanu VashistDepartment of Research, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.
Vidya KrishnaDepartment of Research, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer patients, especially those receiving cytotoxic therapy, are assumed to have a higher probability of death from COVID-19. We have conducted this study to identify the Case Fatality Rate (CFR) in cancer patients with COVID-19 and have explored the relationship of various clinical factors to mortality in our patient cohort.

methodsAll confirmed cancer cases presented to the hospital from June 8 to August 20, 2020, and developed symptoms/radiological features suspicious of COVID-19 were tested by Real-time polymerase chain reaction assay and/or cartridge-based nucleic acid amplification test from a combination of naso-oropharyngeal swab for SARS-CoV-2. Clinical data, treatment details, and outcomes were assessed from the medical records.

resultsOf the total 3,101 cancer patients admitted to the hospital, 1,088 patients were tested and 186 patients were positive for SARS-CoV-2. The CFR in the cohort was 27/186 (14.52%). Univariate analysis showed that the risk of death was significantly associated with the presence of any comorbidity (OR: 2.68; (95% CI [1.13-6.32]);

conclusionTo the best of our knowledge, this is the first study from India reporting the CFR, clinical associations, and risk factors for mortality in SARS-CoV-2 infected cancer patients. Our study shows that the frequency of COVID-19 in cancer patients is high. Recent anticancer therapies are not associated with mortality. Pre-existing comorbidities, especially diabetes, multiple comorbidities, and severe symptoms at presentation are significantly linked with COVID-19 related death in the cohort.

Indexed as

CancerCase fatality rateComorbiditiesSARS-CoV-2

Identifiers

PMID33552716
PMCPMC7827973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.