Evidence map›Paper›PMID 33552685›Full record

ArticleOncoimmunology2021

Pembrolizumab as a monotherapy or in combination with platinum-based chemotherapy in advanced non-small cell lung cancer with PD-L1 tumor proportion score (TPS) ≥50%: real-world data.

Elizabeth Dudnik, Mor Moskovitz, Yakir Rottenberg, Anastasiya Lobachov, Rinat Mandelboim, Tzippy Shochat, Damien Urban, Mira Wollner, Hovav Nechushtan, Ofer Rotem and 4 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Elizabeth DudnikThoracic Cancer Service, Davidoff Cancer Center, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.ORCID 0000-0001-6971-3576
Mor MoskovitzOncology Department, Thoracic Cancer Service, Rambam Health Care Campus, Haifa, Israel.
Yakir RottenbergOncology Department, Hadassah Medical Center, Jerusalem, Israel.
Anastasiya LobachovThoracic Cancer Service, Institute of Oncology, Sheba Medical Center, Ramat Gan, Israel.
Rinat MandelboimThoracic Cancer Service, Davidoff Cancer Center, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.
Tzippy ShochatStatistical Consulting Unit, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.
Damien UrbanSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Mira WollnerOncology Department, Thoracic Cancer Service, Rambam Health Care Campus, Haifa, Israel.
Hovav NechushtanOncology Department, Hadassah Medical Center, Jerusalem, Israel.
Ofer RotemThoracic Cancer Service, Davidoff Cancer Center, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.
Alona ZerThoracic Cancer Service, Davidoff Cancer Center, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.
Sameh DaherThoracic Cancer Service, Institute of Oncology, Sheba Medical Center, Ramat Gan, Israel.
Jair BarSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Israel Lung Cancer Group
Tel Aviv University · ILRabin Medical Center · ILHebrew University of Jerusalem · ILRambam Health Care Campus · ILSheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both pembrolizumab (P) and combination of pembrolizumab with platinum-based chemotherapy (PCT) represent standard 1

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAntibodies, Monoclonal, HumanizedB7-H1 AntigenFemaleHumansIn Situ Hybridization, FluorescencePlatinumProspective StudiesProto-Oncogene MasProto-Oncogene ProteinsAntibodies, Monoclonal, HumanizedB7-H1 AntigenMAS1 protein, humanpembrolizumabPlatinumProto-Oncogene MasProto-Oncogene Proteinslung cancerPD-L1Pembrolizumabpembrolizumab chemotherapyreal world

Identifiers

PMID33552685
PMCPMC7849771
OpenAlexW3126407524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.