Evidence map›Paper›PMID 33552606›Full record

ArticleCase reports in ophthalmological medicine2021

Conjunctival Tarsal Actinic Keratosis Treated with Interferon Alfa-2b: A Rare Case Report and Literature Review.

Mónica Gimeno-Carrero, María-Jesús Suárez-Fernández, Beatriz Alonso-Martín, Almudena de-Pablo-Cabrera, María-Concepción Garrido-Ruíz, Enrique Mencía-Gutiérrez

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In one paragraph

Article in Case reports in ophthalmological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mónica Gimeno-CarreroOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0001-9123-4643
María-Jesús Suárez-FernándezOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0002-4842-3745
Beatriz Alonso-MartínOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0003-2478-1051
Almudena de-Pablo-CabreraOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0003-4591-0860
María-Concepción Garrido-RuízPathology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0002-5400-0693
Enrique Mencía-GutiérrezOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, Spain.ORCID https://orcid.org/0000-0001-5314-6976
Research Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjunctival neoplasia is one of the most frequent tumors in the eye. Actinic keratosis (AK) or solar keratosis is a precancerous lesion that is included with other epithelial tumors. This alteration does not break the basal membrane. There is enough evidence of successful outcomes to consider interferon alfa-2b (IFN alfa-2b) as the first choice of treatment for this type of tumors. In addition, side effects are mild and uncommon. We report a case in an 83-year-old woman who was referred to evaluate a leukoplakia in the tarsal conjunctiva of the lower left eyelid that measured 1 cm in diameter. Pathological study revealed AK. After the INF alfa-2b treatment, we observed conjunctival hyperemia, noninfiltrated upper nasal de-epithelization, and inferior nasal bulla. AK with presentation in conjunctiva is rarely described and in tarsal conjunctiva is exceptional. It is the first case published with only tarsal conjunctiva affectation.

Identifiers

PMID33552606
PMCPMC7847316
OpenAlexW3125433379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.