Evidence map›Paper›PMID 33552569›Full record

ArticleCentral European journal of urology2020

Value of separate tumor base biopsy in transurethral resection of bladder tumors.

Ben Valery Sionov, Matvey Tsivian, Tarek Taha, Roman Bass, Alexander Kheifets, Abraham Ami Sidi, Alexander Tsivian

Open access · greenAbstract read
In one paragraph

Article in Central European journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ben Valery SionovDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Matvey TsivianDepartment of Urology, Mayo Clinic, Rochester, MN, USA.
Tarek TahaDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Roman BassDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Alexander KheifetsDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Abraham Ami SidiDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Alexander TsivianDepartment of Urologic Surgery, Edith Wolfson Medical Center, Holon, Israel.
Tel Aviv University · ILMayo Clinic in Arizona · USWolfson Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of our study was to evaluate whether a biopsy from the tumor base after transurethral resection of bladder tumor (TURBT) has an impact on subsequent management of patients with bladder tumors. While tumor base biopsy at the completion of TURBT is a common practice, there is no definition of its role within the major international professional guidelines. MATERIAL AND

methodsWe retrospectively reviewed the records of consecutive patients undergoing TURBT between 2015 and 2019 at our institution. We recorded demographic and tumor characteristics of initial TURBT, tumor base biopsy and restaging TURBT pathology outcomes. The pathologic outcomes were correlated to assess the additional value of a separate tumor base biopsy.

resultsA total of 532 patients underwent TURBT. A separate tumor base biopsy after completion of TURBT was performed in 154 patients. The mean patient's age was 72.8 ±11.7 years (range 48-94) and 119 (77.2%) were men. In 40 patients (25.9%) muscle was absent in the pathological specimen of the tumor resection. Muscle was present in all but 6 (3.9%) tumor base biopsies. Of the 33 patients who underwent repeated transurethral resection for pT1 tumors, 2 had residual low-grade pTa, 1 had residual high-grade pT1, and 3 patients were upstaged to pT2.

conclusionsAlthough tumor base biopsy at the completion of TURBT is a common practice, our analysis fails to demonstrate any tangible benefit in the staging of bladder tumors. In our experience tumor base biopsy did not change the management in patients with superficial or muscle invasive disease.

Indexed as

biopsybladder cancerevaluation studystagingtransurethral resectiontumor base

Identifiers

PMID33552569
PMCPMC7848826
OpenAlexW3127141572

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.