Evidence map›Paper›PMID 33552528›Full record

ArticleCanadian journal of kidney health and disease2021

Outcomes of an Inpatient Dialysis Start in Patients With Kidney Graft Failure: A Population-Based Multicentre Cohort Study.

Kyla L Naylor, Gregory A Knoll, Eric McArthur, Amit X Garg, Ngan N Lam, Bonnie Field, Leah E Getchell, Emma Hahn, S Joseph Kim

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Kyla L NaylorICES, ON, Canada.ORCID https://orcid.org/0000-0002-5304-8038
Gregory A KnollDepartment of Medicine (Nephrology), University of Ottawa and Ottawa Hospital Research Institute, ON, Canada.
Eric McArthurICES, ON, Canada.
Ngan N LamDivision of Nephrology, University of Alberta, Edmonton, Canada.
Bonnie FieldRenal Patient and Family Advisory Council, London Health Sciences Centre, ON, Canada.
Leah E GetchellDivision of Nephrology, London Health Sciences Centre, ON, Canada.
Emma HahnDivision of Nephrology, London Health Sciences Centre, ON, Canada.
S Joseph KimDivision of Nephrology, Toronto General Hospital, University Health Network and University of Toronto, ON, Canada.
London Health Sciences Centre · CAWestern University · CAUniversity Health Network · CAUniversity of Alberta · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe frequency and outcomes of starting maintenance dialysis in the hospital as an inpatient in kidney transplant recipients with graft failure are poorly understood.

objectiveTo determine the frequency of inpatient dialysis starts in patients with kidney graft failure and examine whether dialysis start status (hospital inpatient vs outpatient setting) is associated with all-cause mortality and kidney re-transplantation.

designPopulation-based cohort study.

settingWe used linked administrative healthcare databases from Ontario, Canada. PATIENTS: We included 1164 patients with kidney graft failure from 1994 to 2016. MEASUREMENTS: All-cause mortality and kidney re-transplantation.

methodsThe cumulative incidence function was used to calculate the cumulative incidence of all-cause mortality and kidney re-transplantation, accounting for competing risks. Subdistribution hazard ratios from the Fine and Gray model were used to examine the relationship between inpatient dialysis starts (vs outpatient dialysis start [reference]) and the dependent variables (ie, mortality or re-transplant).

resultsWe included 1164 patients with kidney graft failure. More than half (55.8%) of patients with kidney graft failure, initiated dialysis as an inpatient. Compared with outpatient dialysis starters, inpatient dialysis starters had a significantly higher cumulative incidence of mortality and a significantly lower incidence of kidney re-transplantation ( LIMITATIONS: Possibility of residual confounding and unable to determine inpatient dialysis starts that were unavoidable.

conclusionsIn this study we identified that most patients with kidney graft failure had inpatient dialysis starts, which was associated with an increased risk of mortality. Further research is needed to better understand the reasons for an inpatient dialysis start in this patient population.

Indexed as

inpatient dialysis startkidney graft failurekidney re-transplantationmortalityoutpatient dialysis start

Identifiers

PMID33552528
PMCPMC7841655
OpenAlexW3121557175

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.