Evidence map›Paper›PMID 33552462›Full record

ArticleParkinson's disease2021

The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type.

Xiaohang Li, Chengju Wang, Xueming Zhang, Wanli Zhang, Binbin Deng, Xun Wang, Huanjie Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parkinson's disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiaohang LiYanzhou Branch of Affiliated Hospital of Jining Medical University, Jining 272100, China.ORCID https://orcid.org/0000-0003-0249-2400
Chengju WangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID https://orcid.org/0000-0001-6026-1278
Xueming ZhangThe First People's Hospital of Ningyang County, Taian 271000, China.ORCID https://orcid.org/0000-0003-0957-8549
Wanli ZhangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID https://orcid.org/0000-0002-6401-0342
Binbin DengDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID https://orcid.org/0000-0002-4058-0738
Xun WangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID https://orcid.org/0000-0002-2081-9422
Huanjie HuangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID https://orcid.org/0000-0002-2198-5721
Wenzhou Medical University · CNAffiliated Hospital of Jining Medical University · CNThe First People's Hospital of Guiyang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson's disease (PD) and multiple system atrophy P-type (MSA-P) and to analyze their value as a differential diagnostic method.

methodsThe data of 30 healthy people, 58 PD patients, and 52 MSA-P patients from the First Affiliated Hospital of Wenzhou Medical University were collected. Electrophysiological bulbocavernosus reflex (BCR) and sympathetic skin response (SSR) were evaluated using the Keypoint EMG/EP system. The latency period, amplitude, and extraction rate of BCR and SSR were compared between the control, PD, and MSA-P groups.

resultsThe incidence of the related autonomic damage in the PD group was lower than that of the MSA-P group. For BCR, the latency period was shorter and the amplitude and elicitation rates were lower in the PD group than in the MSA-P group. For SSR, the latency period was longer in the MSA-P and PD groups than in the control group, but the difference was not statistically significant.

conclusionSSR cannot be used to assess autonomic nerve function. PD patients can have clinical symptoms similar to those of MSA-P patients, but the incidence is lower. Both MSA-P and PD patients have a damage to the BCR arc, but the MSA-P patients have a more severe damage.

Identifiers

PMID33552462
PMCPMC7843193
OpenAlexW3124948106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.