ArticleFrontiers in immunology2020
Dim Light at Night Impairs Daily Variation of Circulating Immune Cells and Renal Immune Homeostasis.
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 40 citations in OpenAlex.
- The circadian architecture of tumor immunity: mechanistic insights and treatment strategies.Biomarker research · 2026Review
- Effect of external cues on clock-driven protection from influenza A infection.The Journal of clinical investigation · 2025Article
- Effect of gestational exposure to dim light at night on the behavior of rat dams and offspring.Scientific reports · 2025Article
- Lipid metabolic adaptations during inflammation are controlled by the circadian clock and impaired by light at night.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Influence of envenomation timing on peripheral immune and oxidative responses in experimental scorpion envenomation.The journal of venomous animals and toxins including tropical diseases · 2025Article
- Article
- Dim light at night shifts microglia to a pro-inflammatory state after cerebral ischemia, altering stroke outcome in mice.Experimental neurology · 2024Article
- Artificial light at night suppresses the day-night cardiovascular variability: evidence from humans and rats.Pflugers Archiv : European journal of physiology · 2024Review
- Impact of Long-Lasting Environmental Factors on Regulation Mediated by the miR-34 Family.Biomedicines · 2024Review
- Molecular mechanisms of artificial light at night affecting circadian rhythm disturbance.Archives of toxicology · 2024Review
- Chronodisruption of the acute inflammatory response by night lighting in rats.Scientific reports · 2023Article
- Acute Circadian Disruption Due to Constant Light Promotes Caspase 1 Activation in the Mouse Hippocampus.Cells · 2023Article
- Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.Antioxidants (Basel, Switzerland) · 2023Article
- Disturbances of Hormonal Circadian Rhythms by Light Pollution.International journal of molecular sciences · 2023Review
- Light at night and cause-specific mortality risk in Mainland China: a nationwide observational study.BMC medicine · 2023Article
- Circadian lifestyle determinants of immune checkpoint inhibitor efficacy.Frontiers in oncology · 2023Review
- Circadian metabolism regulates the macrophage inflammatory response.Life metabolism · 2022Review
- Chronic exposure to dim light at night disrupts cell-mediated immune response and decreases longevity in aged female mice.Chronobiology international · 2022Article
- Artificial Dim Light at Night during Pregnancy Can Affect Hormonal and Metabolic Rhythms in Rat Offspring.International journal of molecular sciences · 2022Article
- Circadian Disruption and Consequences on Innate Immunity and Inflammatory Response.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dim light at night (dLAN) has become a pervasive part of the modern world, and growing evidence shows its association with increased health risks. Though this link is attributed to a disturbed circadian clock, the underlying mechanisms that can explain how circadian disruption from dLAN causes negative health effects remain unclear. Here, we exposed rats to a light-dark cycle (12:12 h) with low-intensity light at night (~2 lx) for 2 and 5 weeks and explored the steady-state pattern of circulating immune cells and renal immune-related markers, which are well controlled by the circadian clock. After 5 weeks, dLAN impaired the daily variation in several types of white blood cells, especially monocytes and T cells. Two-week dLAN caused a reduction in blood monocytes and altered gene expression of macrophage marker
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.