Evidence map›Paper›PMID 33552065›Full record

ArticleFrontiers in immunology2020

Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic

Isabella-Maria Giese, Marie-Christin Schilloks, Roxane L Degroote, Maria Weigand, Simone Renner, Eckhard Wolf, Stefanie M Hauck, Cornelia A Deeg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Altered B cell metabolic pathways characterize type 1 diabetes progression.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Increasing HbA1c is associated with reduced CD8Cellular and molecular life sciences : CMLS · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Greasing the inflammatory pathogenesis of viral pneumonias in diabetes.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. CD8Frontiers in immunology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Isabella-Maria GieseChair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Marie-Christin SchilloksChair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Roxane L DegrooteChair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Maria WeigandChair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Simone RennerChair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Eckhard WolfChair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Stefanie M HauckGerman Center for Diabetes Research (DZD), Neuherberg, Germany.
Cornelia A DeegChair of Physiology, Department of Veterinary Sciences, LMU Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DEGerman Center for Diabetes Research · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People with diabetes mellitus have an increased risk for infections, however, there is still a critical gap in precise knowledge about altered immune mechanisms in this disease. Since diabetic

Indexed as

Cell ProliferationLymphocyte ActivationAnimalsAnimals, Genetically ModifiedAnnexin A1Blood GlucoseCells, CulturedDiabetes MellitusDisease Models, AnimalGlycolysisInsulinMitochondriaMitogensOxygen ConsumptionPhenotypeSus scrofaAnnexin A1Blood GlucoseInsulinMitogensanimal model(s)annexin A1cell metabolismdiabetes mellitusimpaired immune cell functionPHAproliferationT cells

Identifiers

PMID33552065
PMCPMC7862560
OpenAlexW3123223563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.