Evidence map›Paper›PMID 33552033›Full record

ArticleFrontiers in microbiology2020

Biogenic Silver Nanoparticles Can Control

Idessania Nazareth Costa, Mayara Ribeiro, Priscila Silva Franco, Rafaela José da Silva, Thádia Evelyn de Araújo, Iliana Claudia Balga Milián, Luana Carvalho Luz, Pâmela Mendonça Guirelli, Gerson Nakazato, José Roberto Mineo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Vaccines · 2025
    Review
  2. Article
  3. Pathogens (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Galectin-3 plays a key role in controlling infection byFrontiers in cellular and infection microbiology · 2024
    Article
  8. Article
  9. Modeling the human placental barrier to understandFrontiers in cellular and infection microbiology · 2023
    Review
  10. Inhibition ofFrontiers in cellular and infection microbiology · 2022
    Article
  11. Article
  12. Advances inVaccines · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Idessania Nazareth CostaLaboratory of Immunoparasitology of Neglected Diseases and Cancer, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
Mayara RibeiroLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Priscila Silva FrancoLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Rafaela José da SilvaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Thádia Evelyn de AraújoLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Iliana Claudia Balga MiliánLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Luana Carvalho LuzLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Pâmela Mendonça GuirelliLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Gerson NakazatoLaboratory of Immunoparasitology of Neglected Diseases and Cancer, Center of Biological Sciences, State University of Londrina, Londrina, Brazil.
José Roberto MineoLaboratory of Immunoparasitology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Tiago W P MineoLaboratory of Immunoparasitology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Bellisa Freitas BarbosaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Eloisa Amália Vieira FerroLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Universidade Federal de Uberlândia · BRUniversidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of sulfadiazine and pyrimethamine plus folinic acid is the conventional treatment for congenital toxoplasmosis. However, this classical treatment presents teratogenic effects and bone marrow suppression. In this sense, new therapeutic strategies are necessary to reduce these effects and improve the control of infection. In this context, biogenic silver nanoparticles (AgNp-Bio) appear as a promising alternative since they have antimicrobial, antiviral, and antiparasitic activity. The purpose of this study to investigate the action of AgNp-Bio in BeWo cells, HTR-8/SVneo cells and villous explants and its effects against

Indexed as

congenital toxoplasmosisnanoparticles treatmentplacentaToxoplasma gondiitrophoblast

Identifiers

PMID33552033
PMCPMC7858645
OpenAlexW3122498470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.