Evidence map›Paper›PMID 33551989›Full record

ReviewFrontiers in endocrinology2020

Advances on circRNAs Contribute to Carcinogenesis and Progression in Papillary Thyroid Carcinoma.

Xiaoqin Xu, Jiexian Jing

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiaoqin XuDepartment of Etiology, Shanxi Cancer Hospital, Taiyuan, China.
Jiexian JingDepartment of Etiology, Shanxi Cancer Hospital, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In view of the highly increased prevalence of papillary thyroid carcinoma (PTC) year by year, it is of great importance to explore new molecular targets for anticancer strategies. Emerging evidence indicates that circular RNAs (circRNAs), characterized by a closed-loop structure and high stability, play important roles in tumorigenesis and development of human cancer by regulating multiple complex biological processes, such as cellular proliferation, metastasis, and metabolism. A comprehensive understanding of the roles of circRNAs will facilitate the development of promising future therapeutic strategies for treating cancers, including PTC. In this paper, we review the profile of circRNA in PTC, its regulatory roles, and the pathological mechanism as well as their related clinical significance. In addition, challenges of this specific field are discussed.

Indexed as

Biomarkers, TumorCarcinogenesisHumansPrognosisRNA, CircularSignal TransductionThyroid Cancer, PapillaryThyroid NeoplasmsBiomarkers, TumorRNA, CircularceRNAcharacteristicscircRNAdiagnosispapillary thyroid carcinomaprognosissignaling pathway

Identifiers

PMID33551989
PMCPMC7859613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.