ArticleFrontiers in physiology2020
Cerebral Hemodynamic and Neurotrophic Factor Responses Are Dependent on the Type of Exercise.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05131217 (Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults
Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Vascular aging as a driver of organ dysfunction and systemic aging.Nature cardiovascular research · 2026Review
- Mechanisms of Exercise-Mediated Regulation of the Gut-Brain Axis in Parkinson's Disease.Nutrients · 2026Review
- Cerebrovascular Function in Women With Polycystic Ovary Syndrome: A Pilot Multi-Parameter Magnetic Resonance Imaging Study.Clinical endocrinology · 2026Article
- Cerebral blood velocity responses during and after sprint interval exercise in healthy young adults.Physiological reports · 2026Article
- Walking to protect against cognitive decline: the role of APOE genotype and sex.Biology of sex differences · 2026Article
- Brain derived neurotrophic factor and secreted amyloid precursor protein-α response to moderate and high intensity exercise.Physiological reports · 2025Article
- Effects of interval versus continuous exercise on cerebral vascular flow-mediated dilatation in young healthy males.Physiological reports · 2025Article
- Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson's disease.Frontiers in aging neuroscience · 2025Review
- Middle cerebral artery blood velocity and end-tidal carbon dioxide responses to moderate intensity cycling in children, adolescents, and adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Exercise Reshapes the Brain: Molecular, Cellular, and Structural Changes Associated with Cognitive Improvements.Molecular neurobiology · 2023Review
- Neurovascular coupling and cerebrovascular hemodynamics are modified by exercise training status at different stages of maturation during youth.American journal of physiology. Heart and circulatory physiology · 2023Article
- Examining the Interaction between Exercise, Gut Microbiota, and Neurodegeneration: Future Research Directions.Biomedicines · 2023Review
- A Shorter-Bout of HIIT Is More Effective to Promote Serum BDNF and VEGF-A Levels and Improve Cognitive Function in Healthy Young Men.Frontiers in physiology · 2022Article
- Cerebrovascular response to an acute bout of low-volume high-intensity interval exercise and recovery in young healthy adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Lactate as Potential Mediators for Exercise-Induced Positive Effects on Neuroplasticity and Cerebrovascular Plasticity.Frontiers in physiology · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined acute cerebral hemodynamic and circulating neurotrophic factor responses to moderate intensity continuous exercise (MICT), guideline-based high intensity interval exercise (HIIT), and sprint interval exercise (SIT). We hypothesized that the pattern of middle cerebral artery velocity (MCAv) response would differ between interval and continuous exercise, with SIT inducing the smallest increase from rest, while increases in neurotrophic factors would be intensity-dependent. In a randomized crossover design, 24 healthy adults (nine females) performed three exercise protocols: (i) MICT (30 min), (ii) HIIT (4 × 4 min at 85% HR
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.