Evidence map›Paper›PMID 33551824›Full record

ArticleFrontiers in physiology2020

Genetic Ablation of G Protein-Gated Inwardly Rectifying K

Isabelle Bidaud, Alicia D'Souza, Gabriella Forte, Eleonora Torre, Denis Greuet, Steeve Thirard, Cali Anderson, Antony Chung You Chong, Angelo G Torrente, Julien Roussel and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Aging and sinus node dysfunction: mechanisms and future directions.Clinical science (London, England : 1979) · 2025
    Review
  6. G protein-gated inwardly rectifying KHistology and histopathology · 2025
    Review
  7. Article
  8. Article
  9. Relevance ofInternational journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Isabelle BidaudInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Alicia D'SouzaDivision of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Gabriella ForteDivision of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Eleonora TorreInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Denis GreuetInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Steeve ThirardInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Cali AndersonDivision of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
Antony Chung You ChongInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Angelo G TorrenteInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Julien RousselInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Kevin WickmanDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, United States.
Mark R BoyettDivision of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Matteo E MangoniInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Pietro MesircaInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Inserm · FRUniversité de Montpellier · FRUniversity of Manchester · GBCentre National de la Recherche Scientifique · FRInstitut de Génomique Fonctionnelle · FRUniversity of Copenhagen · DKUniversity of Minnesota · US

Funding

The role of RGS proteins in the parasympathetic control of heart rateR01HL105550 · NHLBI · UNIVERSITY OF MINNESOTA · PI MARTEMYANOV, KIRILL A., WICKMAN, KEVIN D · 2011 to 2018
$3.2M
British Heart Foundation FS/19/1/34035NHLBI NIH HHS R01 HL105550
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bradycardiaendurance athletesG-protein-gated inwardly rectifying potassium 4 (Girk4)hyperpolarization-activated cyclic nucleotide-gated 4 (HCN4) channelsinoatrial node

Identifiers

PMID33551824
PMCPMC7857143
OpenAlexW3125406550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.