ArticleFrontiers in pharmacology2020
Modulation of the Gut Microbiota and Liver Transcriptome by Red Yeast Rice and Monascus Pigment Fermented by Purple Monascus SHM1105 in Rats Fed with a High-Fat Diet.
Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Dual modulation of lipid and glucose metabolism by a nutraceutical combination in patients at cardiometabolic risk: results from a multicenter randomized controlled trial.Cardiovascular diabetology · 2025 · on this mapTrial
- Hypocholesterolemic agents and the gut microbiota: a review of interactions and modulatory activity.Pharmacological reports : PR · 2026Review
- Research progress of biological processing of traditional Chinese medicine:fermentation and sprouting.Chinese medicine · 2026Review
- Potential Role of Red Yeast Rice in the Prevention and Treatment of Alzheimer's Disease.International journal of medical sciences · 2026Review
- Gut microbiota related steroid hormone biosynthesis provide novel insights into high-salt diet related renal injury vit gut-kidney axis.BMC microbiology · 2025Article
- A Comprehensive Investigation of Lipid Profile During the Solid-State Fermentation of Rice byFoods (Basel, Switzerland) · 2025Article
- Monascus red pigment influence on hydroxyapatite nanoparticles-mediated renal toxicity in rats.Scientific reports · 2025Article
- Red yeast rice extract improves lipid metabolism by modulating gut microbiota in high-fat diet mice.Frontiers in pharmacology · 2025Article
- Review
- Article
- Proteomics and Its Combined Analysis with Transcriptomics: Liver Fat-Lowering Effect of Taurine in High-Fat Fed Grouper (Animals : an open access journal from MDPI · 2024Article
- Modified Zuo Gui Wan Ameliorates Ovariectomy-Induced Osteoporosis in Rats by Regulating the SCFA-GPR41-p38MAPK Signaling Pathway.Drug design, development and therapy · 2024Article
- Autoclaving-treated germinated brown rice relieves hyperlipidemia by modulating gut microbiota in humans.Frontiers in nutrition · 2024Article
- Hyperlipidaemia treatment and gut microbiology.Frontiers in microbiology · 2024Review
- Rhabdomyolysis-induced acute kidney injury after administration of a red yeast rice supplement: A case report.World journal of clinical cases · 2023Article
- Integrated Metabolomic and Transcriptomic Analysis Reveals Potential Gut-Liver Crosstalks in the Lipogenesis of Chicken.Animals : an open access journal from MDPI · 2023Article
- Untargeted Gut Metabolomics to Delve the Interplay between Selenium Supplementation and Gut Microbiota.Journal of proteome research · 2022Article
- Comprehensive evaluation of the mechanism ofFrontiers in cellular and infection microbiology · 2022Article
- Cooked Adzuki Bean Reduces High-Fat Diet-Induced Body Weight Gain, Ameliorates Inflammation, and Modulates Intestinal Homeostasis in Mice.Frontiers in nutrition · 2022Article
- Diet-gut microbiota interactions on cardiovascular disease.Computational and structural biotechnology journal · 2022Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperlipidemia can easily cause atherosclerosis and induce cardiovascular and cerebrovascular diseases. Red yeast rice (RYR) contains a variety of active ingredients and is commonly used as medicine and food, and has pharmacological effects such as lowering blood lipids. In this study, we select Monascus strain SHM1105 with a high yield of Monacolin K and monascus pigment (PIG), and studied the effects of the RYR and PIG fermented by this strain on blood lipids, intestinal flora, and liver transcriptome in hyperlipidemia model rats. The experimental results show that, compared with the high-fat model group, the weight growth rate, liver weight ratio, kidney weight ratio, spleen weight ratio, and fat weight ratio of rats in the gavage lovastatin (LOV), RYR, and PIG group were all significantly decreased (
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