Evidence map›Paper›PMID 33551797›Full record

ArticleFrontiers in pharmacology2020

Impact of Implementing CYP2C19 Genotype-Guided Antiplatelet Therapy on P2Y

Yi Zhang, Xiu-Jin Shi, Wen-Xing Peng, Jia-Lun Han, Bai-Di Lin, Ru Zhang, Yun-Nan Zhang, Jia-Lin Yan, Juan-Juan Wei, Yi-Fan Wang and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06665919 (Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06665919 nacompletednot on this mapstarted 2023, after this paper: background citation

Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI

TypeinterventionalSponsorVistamedi Ltd.Ran2023 to 2025Enrolled283ConditionsCoronary Artery Disease, Clopidogrel Resistance, Coronary Thrombosis, Adverse Cardiac EventsArmsCYP2C19 Genotype-Guided Clopidogrel Treatment, CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel, The Conventional Clopidogrel Treatment
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Genetic Determinants of Response to P2YInterventional cardiology clinics · 2024
    Review
  10. Article
  11. From genes to drugs:Frontiers in pharmacology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Evaluation of race and ethnicity disparities in outcome studies ofFrontiers in cardiovascular medicine · 2022
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Yi ZhangDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiu-Jin ShiDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Wen-Xing PengDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jia-Lun HanDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Bai-Di LinDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Ru ZhangDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yun-Nan ZhangDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jia-Lin YanDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Juan-Juan WeiDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yi-Fan WangDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Su-Wei ChenDepartment of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Nan NanDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhen-Wei FangDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yong ZengDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yang LinDepartment of Pharmacy, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Beijing Anzhen Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute coronary syndromeclopidogrelCYP2C19gene-guided antiplatelet therapyticagrelor

Identifiers

PMID33551797
PMCPMC7854467
OpenAlexW3124534407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.