ReviewFrontiers in aging neuroscience2020
Cognitive Reserve in Model Systems for Mechanistic Discovery: The Importance of Longitudinal Studies.
Review in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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Who cites it
42 citing papers in PubMed.
- Cognitive reserve and adaptive resilience: a conceptual analysis of a cross-species framework for neuropsychology and cognitive aging.Frontiers in psychology · 2026Review
- Multimodal anti fraud education improves cognitive emotional and behavioral engagement in older adults.Scientific reports · 2025Article
- Early Onset Memory Deficit of WMI Rats Compared to Their Nearly Isogenic WLIs Is Reversed by Enriched Environment in Females.Genes, brain, and behavior · 2025Article
- A comprehensive review: role of smokeless tobacco consumption as a risk factor for diabetes mellitus.Acta diabetologica · 2025Review
- Age-related synaptic signatures of brain and cognitive reserve in the rat hippocampus and parahippocampal regions.Neurobiology of aging · 2025Article
- Sex, senescence, senolytics, and cognition.Frontiers in aging neuroscience · 2025Review
- Adolescent Alcohol and the Spectrum of Cognitive Dysfunction in Aging.Advances in experimental medicine and biology · 2025Review
- Age-related effects on a hierarchical structure of canine cognition.GeroScience · 2024Article
- Experimental laboratory models as tools for understanding modifiable dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Cognitive trajectories in longitudinally trained 3xTg-AD mice.Physiology & behavior · 2024Article
- A measure of modifiable lifestyle factors shaping subjective cognitive reserve in the general population.Frontiers in psychology · 2024Article
- Failure of senolytic treatment to prevent cognitive decline in a female rodent model of aging.Frontiers in aging neuroscience · 2024Article
- How is Big Data reshaping preclinical aging research?Lab animal · 2023Review
- Exploring the Role of Neuroplasticity in Development, Aging, and Neurodegeneration.Brain sciences · 2023Review
- Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression.Brain : a journal of neurology · 2023Article
- Lower and higher volumes of physical exercise build up brain reserves against memory deficits triggered by a head injury in mice.Experimental neurology · 2023Article
- Open science and data sharing in cognitive neuroscience with MouseBytes and MouseBytes.Scientific data · 2023Article
- Skin Autofluorescence Mirrors Surrogate Parameters of Vascular Aging: An Enable Study.Nutrients · 2023Article
- The Association Between Temporal Atrophy and Episodic Memory Is Moderated by Education in a Multi-Center Memory Clinic Sample.Journal of Alzheimer's disease : JAD · 2023Article
- Age-related decline in cognitive flexibility is associated with the levels of hippocampal neurogenesis.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The goal of this review article is to provide a resource for longitudinal studies, using animal models, directed at understanding and modifying the relationship between cognition and brain structure and function throughout life. We propose that forthcoming longitudinal studies will build upon a wealth of knowledge gleaned from prior cross-sectional designs to identify early predictors of variability in cognitive function during aging, and characterize fundamental neurobiological mechanisms that underlie the vulnerability to, and the trajectory of, cognitive decline. Finally, we present examples of biological measures that may differentiate mechanisms of the cognitive reserve at the molecular, cellular, and network level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.