ReviewFrontiers in neural circuits2020
Top-Down Inference in the Auditory System: Potential Roles for Corticofugal Projections.
Review in Frontiers in neural circuits, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Structural connectivity of auditory-linguistic brain networks predicts success in speech categorization and listening in noise.Neuroscience · 2026Article
- Sound-evoked auditory neurophysiological signals are a window into prodromal functional differences in a preclinical model of Alzheimer's disease.Scientific reports · 2026Article
- Effects of Stimulus Complexity on the Phonemic Restoration Effect.Audiology research · 2026Article
- Circuit architecture and axonal branching in the efferent auditory system.Hearing research · 2026Review
- Neuronal mechanisms underlying binaural performance with cochlear implant in single-sided deafness: a [European journal of nuclear medicine and molecular imaging · 2026Article
- Relationships Between Autistic Trait Dimensions and Speech Understanding, Affective Sound Intolerance, and Self-Reported Hearing Difficulties.Autism in adulthood · 2026Article
- Higher-order brain processes, rather than early processing, underlie sensory problems in ME/CFS: evidence from ERPs.Frontiers in medicine · 2026Article
- Projection-specific Routing of Odor Information in the Olfactory Cortex.bioRxiv : the preprint server for biology · 2025Article
- Neural Correlates of Perceptual Plasticity in the Auditory Midbrain and Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Cortical-subcortical interactions underlie processing of auditory predictions measured with 7T fMRI.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Neural correlates of flexible sound perception in the auditory midbrain and thalamus.bioRxiv : the preprint server for biology · 2024Article
- Normal linear and non-linear cochlear mechanisms and efferent system functioning in individuals with misophonia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Isolating Neural Signatures of Conscious Speech Perception with a No-Report Sine-Wave Speech Paradigm.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A mechanism for deviance detection and contextual routing in the thalamus: a review and theoretical proposal.Frontiers in neuroscience · 2024Article
- Highly branched and complementary distributions of layer 5 and layer 6 auditory corticofugal axons in mouse.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Recurrent Circuits Amplify Corticofugal Signals and Drive Feedforward Inhibition in the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Representations of fricatives in subcortical model responses: Comparisons with human consonant perception.The Journal of the Acoustical Society of America · 2023Article
- Developmental Exposure to Polychlorinated Biphenyls Prevents Recovery from Noise-Induced Hearing Loss and Disrupts the Functional Organization of the Inferior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Perceptual warping exposes categorical representations for speech in human brainstem responses.NeuroImage · 2023Article
- Developmental exposure to polychlorinated biphenyls prevents recovery from noise-induced hearing loss and disrupts the functional organization of the inferior colliculus.bioRxiv : the preprint server for biology · 2023Article
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Authors and funding
2 authors.
Funding
Abstract
It has become widely accepted that humans use contextual information to infer the meaning of ambiguous acoustic signals. In speech, for example, high-level semantic, syntactic, or lexical information shape our understanding of a phoneme buried in noise. Most current theories to explain this phenomenon rely on hierarchical predictive coding models involving a set of Bayesian priors emanating from high-level brain regions (e.g., prefrontal cortex) that are used to influence processing at lower-levels of the cortical sensory hierarchy (e.g., auditory cortex). As such, virtually all proposed models to explain top-down facilitation are focused on intracortical connections, and consequently, subcortical nuclei have scarcely been discussed in this context. However, subcortical auditory nuclei receive massive, heterogeneous, and cascading descending projections at every level of the sensory hierarchy, and activation of these systems has been shown to improve speech recognition. It is not yet clear whether or how top-down modulation to resolve ambiguous sounds calls upon these corticofugal projections. Here, we review the literature on top-down modulation in the auditory system, primarily focused on humans and cortical imaging/recording methods, and attempt to relate these findings to a growing animal literature, which has primarily been focused on corticofugal projections. We argue that corticofugal pathways contain the requisite circuitry to implement predictive coding mechanisms to facilitate perception of complex sounds and that top-down modulation at early (i.e., subcortical) stages of processing complement modulation at later (i.e., cortical) stages of processing. Finally, we suggest experimental approaches for future studies on this topic.
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