ArticleFrontiers in neuroscience2020
Deafness Weakens Interareal Couplings in the Auditory Cortex.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Brain Morphological Modifications in Congenital and Acquired Auditory Deprivation: A Systematic Review and Coordinate-Based Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Alpha oscillatory activity reveals focused-attentional disparity between cochlear implant users and normal hearing listeners.Scientific reports · 2026Article
- Dynamic functional connectivity following cochlear implantation: Predicting speech outcomes and exploring brain network dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Age-Related Hearing Decline and Resting-State Networks.American journal of audiology · 2025Article
- Functional Connectivity Is Stronger Between Unisensory and Multisensory Regions for Nonsimultaneous Judgments of Visual-Tactile Stimuli.Psychophysiology · 2025Article
- Vibrotactile speech cues are associated with enhanced auditory processing in middle and superior temporal gyri.Scientific reports · 2025Article
- Article
- Multidimensional Alternating Kernel Method for cortical layer segmentation in 3D reconstructed histology.MethodsX · 2024Article
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Against cortical reorganisation.eLife · 2023Article
- Crossmodal plasticity in hearing loss.Trends in neurosciences · 2023Review
- Hearing and Cognition in Childhood.Laryngo- rhino- otologie · 2023Article
- Linking Cerebrovascular Dysfunction to Age-Related Hearing Loss and Alzheimer's Disease-Are Systemic Approaches for Diagnosis and Therapy Required?Biomolecules · 2022Review
- Children's Neural Sensitivity to Prosodic Features of Natural Speech and Its Significance to Speech Development in Cochlear Implanted Children.Frontiers in neuroscience · 2022Article
- Deficient Recurrent Cortical Processing in Congenital Deafness.Frontiers in systems neuroscience · 2022Article
- Processing of auditory information in forebrain regions after hearing loss in adulthood: Behavioral and electrophysiological studies in a rat model.Frontiers in neuroscience · 2022Article
- Resting-state EEG reveals global network deficiency in prelingually deaf children with late cochlear implantation.Frontiers in pediatrics · 2022Article
- Changes of the Brain Causal Connectivity Networks in Patients With Long-Term Bilateral Hearing Loss.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The function of the cerebral cortex essentially depends on the ability to form functional assemblies across different cortical areas serving different functions. Here we investigated how developmental hearing experience affects functional and effective interareal connectivity in the auditory cortex in an animal model with years-long and complete auditory deprivation (deafness) from birth, the congenitally deaf cat (CDC). Using intracortical multielectrode arrays, neuronal activity of adult hearing controls and CDCs was registered in the primary auditory cortex and the secondary posterior auditory field (PAF). Ongoing activity as well as responses to acoustic stimulation (in adult hearing controls) and electric stimulation applied via cochlear implants (in adult hearing controls and CDCs) were analyzed. As functional connectivity measures pairwise phase consistency and Granger causality were used. While the number of coupled sites was nearly identical between controls and CDCs, a reduced coupling strength between the primary and the higher order field was found in CDCs under auditory stimulation. Such stimulus-related decoupling was particularly pronounced in the alpha band and in top-down direction. Ongoing connectivity did not show such a decoupling. These findings suggest that developmental experience is essential for functional interareal interactions during sensory processing. The outcomes demonstrate that corticocortical couplings, particularly top-down connectivity, are compromised following congenital sensory deprivation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.