Evidence map›Paper›PMID 33551679›Full record

ArticleMediators of inflammation2021

The Protective Effect of Anthocyanins Extracted from

Li Li, Jun Li, Hui Xu, Fengmei Zhu, Zhijun Li, Hongzhi Lu, Jinrong Zhang, Zhengsheng Yang, Yongsheng Liu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Black Chokeberry Extracts (Molecules (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Effects of Chokeberries (Journal of clinical medicine · 2023
    Article
  15. Article
  16. Review
  17. Chokeberry (Nutrients · 2022
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Li LiDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-8639-413X
Jun LiHebei Normal University of Science and Technology, No. 360, Hebeidajie, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-7344-7511
Hui XuDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-6390-7318
Fengmei ZhuHebei Normal University of Science and Technology, No. 360, Hebeidajie, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-2054-7957
Zhijun LiThe People Hospital of Shanhaiguan, No. 5, Guancheng Road, Shanhaiguan, Qinhuangdao, Hebei, China 066200.ORCID https://orcid.org/0000-0002-4739-5957
Hongzhi LuDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-0195-192X
Jinrong ZhangDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0002-1185-1324
Zhengsheng YangDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0001-6311-9939
Yongsheng LiuDepartment of Internal Medicine, The First Hospital of Qinhuangdao, No. 258 Wenhua Road, Haigang, Qinhuangdao, Hebei, China 066000.ORCID https://orcid.org/0000-0001-7744-3828
First Hospital of Qinhuangdao · CNHebei Normal University of Science and Technology · CNQinhuangdao Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur previous research showed the antioxidant activity of anthocyanins extracted from

methodsAcute renal injury model was initiated by 30 min clamping bilateral renal pedicle and followed by 24-hour reperfusion in C57Bl/6J mice. Four groups of mice were orally pretreated in 50 mg/g/12 h for two weeks with cyanidin-3-arabinoside, cyanidin-3-glucodise, and cyaniding-3-galactoside and anthocyanins (three-cyanidin mixture), respectively, sham-control group and the renal injury-untreated groups only with saline.

resultsThe model resulted in renal dysfunction with high serum creatinine, blood urea nitrogen, and changes in proinflammatory cytokines (TNF-ɑ, IL-1

conclusionthe current study provided the first attempt to investigate the role of anthocyanins purified from

Indexed as

Reperfusion InjuryAnimalsAnthocyaninsAntioxidantsApoptosisArabinonucleosidesBody WeightCaspase 9FruitGalactosidesInflammationKidneyKidney Failure, ChronicLipid PeroxidationMiceMice, Inbred C57BLAnthocyaninsAntioxidantsArabinonucleosidesCaspase 9cyanidincyanidin 3-galactosidecyanidin-3-O-beta-glucopyranosideGalactosides

Identifiers

PMID33551679
PMCPMC7846408
OpenAlexW3122588627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.