ArticleJournal of orthopaedics
Treatment options in PJI - is two-stage still gold standard?
Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06944184 (In Vivo Antibiotic Elution During Two-Stage Knee Revision), which is not on this map. Cited by 44 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
In Vivo Antibiotic Elution During Two-Stage Knee Revision: A Microdialysis Study
Who cites it
44 citing papers in PubMed, 7 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- The effect of extended postoperative oral antibiotic prophylaxis on the reinfection risk following two-stage exchange arthroplasty for hip and knee periprosthetic joint infection: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Outcomes following planned two-stage exchange arthroplasty for periprosthetic joint infections in the United States: a systematic review of the literature.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Comparative reinfection rate of one-stage versus two-stage revision in the management of periprosthetic joint infection following total hip arthroplasty: a meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- Local antibiotic delivery via intra-articular catheter infusion for the treatment of periprosthetic joint infection: a systematic review.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Systematic review and meta-analysis of single-stage vs two-stage revision for periprosthetic joint infection: a call for a prospective randomized trial.BMC musculoskeletal disorders · 2024Pooled it
- Characterizing recurrent infections after one-stage revision for periprosthetic joint infection of the knee: a systematic review of the literature.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Pooled it
- Acute kidney injury in the context of staged revision arthroplasty and the use of antibiotic-laden cement spacers: a systematic review.Journal of orthopaedic surgery and research · 2023Pooled it
- Impact of surface structuring on antibiotic elution from bone cement in two-stage revision for periprosthetic joint infection.BMC musculoskeletal disorders · 2026Article
- Effectiveness and tolerability of low dose clindamycin for treatment of prosthetic joint infections, a retrospective cohort study.BMC infectious diseases · 2026Article
- Revision total elbow arthroplasty for aseptic and septic nonunion of distal humerus fractures: a case series.JSES reviews, reports, and techniques · 2026Article
- Clinical and psychosocial impact of limited mobility during the interstage period of two-stage revision arthroplasty for prosthetic joint infection: a state-of-the-art review.Journal of orthopaedic surgery and research · 2026Review
- Revision of a Dislocated Articulating Antibiotic Hip Spacer as an Alternative to Girdlestone Arthroplasty: A Case Report.Journal of orthopaedic case reports · 2026Article
- Differential impact of single interim spacer exchanges on survival outcomes in two-stage exchange arthroplasty for PJIs: a comparative analysis with minimum 5-year follow-up.BMC musculoskeletal disorders · 2026Article
- Effective therapy for periprosthetic joint infection through sequential application of non-contact low-frequency ultrasonic debridement and antiseptic solutions.Bone & joint research · 2026Article
- Six-Week Protocol for Two-Stage Exchange Arthroplasty in a High-Risk Population.Arthroplasty today · 2026Article
- Retained articulating spacers (1.5 stage) in chronic knee periprosthetic joint infections: an analysis of associate factors and outcomes in a single center cohort of patients.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Observational
- Phage therapy in revision arthroplasty: State of the art and application protocols.Arthroplasty (London, England) · 2026Review
- Reevaluation of surgical strategies for chronic periprosthetic joint infection: a comparison of short-term outcomes between one-stage and two-stage revision.Frontiers in cellular and infection microbiology · 2026Article
- Clinical Evaluation of Two-Stage Revision Total Knee Arthroplasty Using Silicone Mold-Based and Metal Mold-Based Antibiotic-Loaded Knee Spacers: A Comparative Study.Medical journal of the Islamic Republic of Iran · 2026Article
- Management and outcomes of culture-negative periprosthetic joint infection: a systematic review and meta-analysis.Journal of bone and joint infection · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Total knee arthroplasty (TKA) is a successful treatment for osteoarthritis with good clinical outcomes
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.