ReviewInternal medicine (Tokyo, Japan)2022
Adverse Effects of Kampo Medicines.
Review in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Changes in the Quantitative Computed Tomography Values in Drug-associated Interstitial Lung Disease Caused by Non-anticancer Drugs.Internal medicine (Tokyo, Japan) · 2026Article
- Kakkonto-Induced Pneumonitis: A Case Report.Cureus · 2026Article
- A Case of Drug-Induced Cystitis Associated With a Multicomponent Herbal Formulation Involving Yokuinin-To.Cureus · 2026Article
- Extensive idiopathic mesenteric phlebosclerosis presenting as intestinal pseudo-obstruction: A case report.World journal of clinical cases · 2025Article
- Hypercalcemia with the Oral Administration of Active Vitamin D3 and Chinese Herbal Medicine.Internal medicine (Tokyo, Japan) · 2025Article
- Drug-induced liver injury associated with exposure to Hangeshashinto.Journal of general and family medicine · 2025Article
- Water Intoxication Caused by an Overdose of Powdered Herbal Medicine: A Case Report.Clinical case reports · 2025Article
- Similar but Different Three Major Traditional Medicines in East Asia: A Bibliometric Analysis.Chinese journal of integrative medicine · 2025Article
- Trends in Kampo Medicine Usage as Supportive Care During Anticancer Drug Treatment in Japanese Patients: A Nationwide Cohort Analysis from Fiscal Years 2015 to 2021.Current oncology (Toronto, Ont.) · 2025Article
- Management of Chronic Constipation: A Comprehensive Review.Internal medicine (Tokyo, Japan) · 2025Review
- Effect of concomitant use of yokukansan on steady-state blood concentrations of donepezil and risperidone in real-world clinical practice.Neuropsychopharmacology reports · 2024Article
- Effective use ofPCN reports : psychiatry and clinical neurosciences · 2024Article
- Application of Monoclonal Antibodies against Naturally Occurring Bioactive Ingredients.Antibodies (Basel, Switzerland) · 2024Review
- Electropharmacological Characterization of Licorice Using the Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Sheets and the Chronic Atrioventricular Block Dogs.Cardiovascular toxicology · 2023Article
- Identifying Crude Drugs in Kampo Medicines Associated with Drug-Induced Liver Injury Using the Japanese Adverse Drug Event Report Database: A Comprehensive Survey.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Japanese Herbal Medicine (Kampo) as a Possible Treatment for Ischemia With Non-obstructive Coronary Artery Disease.Cureus · 2023Review
- Phlebosclerotic Colitis Associated with Long-term Use of a Chinese Herbal Medicine Containing Gardenia FruitBalkan medical journal · 2022Article
- Torsade de pointes in an older patient with Takotsubo cardiomyopathy caused by licorice-induced pseudoaldosteronism: A case report.Clinical case reports · 2022Article
- Kampo medicines for supportive care of patients with cancer: A brief review.Integrative medicine research · 2022Review
- Drug-induced cystitis caused by herbal medicine (Bofutsushosan).Urology case reports · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes the adverse effects of Kampo medicines. These adverse effects in terms of immunoallergic reactions include interstitial pneumonia, liver injury, allergic cystitis, and drug eruption. Many cases of interstitial pneumonia, liver injury, and allergic cystitis associated with Kampo formulas have been reported to be caused by formulas containing Scutellariae Radix (Scutellaria root, ogon). The known adverse effects linked to overdose of Kampo formulas include pseudoaldosteronism [caused by Glycyrrhizae Radix (licorice, kanzo)], sympathomimetic symptoms [caused by Ephedrae Herba (ephedra, mao)], aconite poisoning [caused by Aconiti Tuber (processed aconite root, bushi and uzu)], and diarrhea [caused by Rhei Rhizoma (rhubarb, daio)]. In recent years, mesenteric phlebosclerosis caused by the long-term administration of Gardeniae Fructus (gardenia fruit, sanshishi) has also been reported. It is necessary to consider these potential adverse effects when prescribing Kampo medicines in clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.