ArticleJournal of epidemiology2021
Updated Trends in Cancer in Japan: Incidence in 1985-2015 and Mortality in 1958-2018-A Sign of Decrease in Cancer Incidence.
Article in Journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed.
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- Cost-effectiveness analysis of chemoradiotherapy compared to surgery in patients with stage I esophageal squamous cell carcinoma in Japan.International journal of clinical oncology · 2026Article
- High incidence of colorectal cancer in Japanese individuals with hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Prognostic impact of diabetes or hypertension in smokers with CRPC receiving enzalutamide or abiraterone.International journal of clinical oncology · 2026Article
- Initial activities and prospects of MIRAY1: a youth-driven, society-endorsed initiative to cultivate future breast cancer physicians.Breast cancer (Tokyo, Japan) · 2026Article
- Interpreting Early-Onset Colorectal Cancer in Japan: A Descriptive Epidemiologic Review Using Public Summary Statistics.Cancer science · 2026Review
- Clinical benefit of locoregional therapy for oligometastasis after surgery for pancreatic cancer: a single center retrospective study.BMC cancer · 2026Article
- Trends in Female Breast Cancer Incidence among Japanese, Korean, and US Populations: An Age-Period-Cohort Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- International trends in cancer mortality revisited: Japan's site-specific progress and remaining challenges until 2024.Japanese journal of clinical oncology · 2026Article
- Predictive performance of breast cancer polygenic risk scores from diverse ancestries: a prospective study in Japanese women.Breast cancer research : BCR · 2026Article
- Article
- Evaluating Behavioral Impacts of School Cancer Education Programs Several Months and Years After Implementation in Japan.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- Nationwide trends in radiotherapy use among older patients with early-stage non-small cell lung cancer in Japan, 2013-2022.Scientific reports · 2026Article
- Oral Squamous Cell Carcinoma Incidence in Japan Based on National Cancer Registry Data 2016-2019.JMA journal · 2026Article
- Acceptability of HPV Vaccination for Daughters: A University Hospital-Wide Questionnaire Survey.Vaccines · 2026Article
- Subsequent primary cancer incidence in cervical cancer survivors: insights from a comprehensive cohort study utilizing combined Japanese population-based cancer registries.Journal of gynecologic oncology · 2026Article
- Efficacy and safety of FOLFOX for Japanese patients with advanced biliary tract cancer as second-line or later chemotherapy (JON2107-B study).International journal of clinical oncology · 2025Article
- Impact of prior solid tumors and their treatment modality on outcomes after allogeneic hematopoietic stem cell transplantation.Bone marrow transplantation · 2025Article
- Forecasting age-standardized incidence rates of gastric cancer from 1990-2050 in Japan according to H. pylori prevalence and eradication scenarios.Journal of gastroenterology · 2025Article
42 more citing papers are in PubMed but not listed here.
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9 authors.
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Abstract
backgroundUnlike many North American and European countries, Japan has observed a continuous increase in cancer incidence over the last few decades. We examined the most recent trends in population-based cancer incidence and mortality in Japan.
methodsNational cancer mortality data between 1958 and 2018 were obtained from published vital statistics. Cancer incidence data between 1985 and 2015 were obtained from high-quality population-based cancer registries maintained by three prefectures (Yamagata, Fukui, and Nagasaki). Trends in age-standardized rates (ASR) were examined using Joinpoint regression analysis.
resultsFor males, all-cancer incidence increased between 1985 and 1996 (annual percent change [APC] +1.1%; 95% confidence interval [CI], 0.7-1.5%), increased again in 2000-2010 (+1.3%; 95% CI, 0.9-1.8%), and then decreased until 2015 (-1.4%; 95% CI, -2.5 to -0.3%). For females, all-cancer incidence increased until 2010 (+0.8%; 95% CI, 0.6-0.9% in 1985-2004 and +2.4%; 95% CI, 1.3-3.4% in 2004-2010), and stabilized thereafter until 2015. The post-2000 increase was mainly attributable to prostate in males and breast in females, which slowed or levelled during the first decade of the 2000s. After a sustained increase, all-cancer mortality for males decreased in 1996-2013 (-1.6%; 95% CI, -1.6 to -1.5%) and accelerated thereafter until 2018 (-2.5%; 95% CI, -2.9 to -2.0%). All-cancer mortality for females decreased intermittently throughout the observation period, with the most recent APC of -1.0% (95% CI, -1.1 to -0.9%) in 2003-2018. The recent decreases in mortality in both sexes, and in incidence in males, were mainly attributable to stomach, liver, and male lung cancers.
conclusionThe ASR of all-cancer incidence began decreasing significantly in males and levelled off in females in 2010.
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