ArticleCancer medicine2021
Nutrition intervention is beneficial to the quality of life of patients with gastrointestinal cancer undergoing chemotherapy in Vietnam.
Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04517708 (Effectiveness of Nutritional Interventions for Cancer Patients Undergoing Chemotherapy), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Nutritional Interventions for Cancer Patients Undergoing Chemotherapy
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Effect of Dietary Interventions on Body Composition and Quality of Life in Stomach Cancer Survivors after Gastrectomy: A Systematic Review.Journal of gastrointestinal cancer · 2026Pooled it
- How quality of life is measured in studies of nutritional intervention: a systematic review.Health and quality of life outcomes · 2024Pooled it
- A clinical study on fall risk assessment and preventive nursing in older adults with non-Hodgkin's lymphoma undergoing chemotherapy-a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- The effects of mindfulness training on emotion and sleep quality in patients with colorectal cancer.Scientific reports · 2025Trial
- Trial
- Neutrophil-to-Lymphocyte Ratio and MUST-Defined Nutritional Risk as Independent Correlates of Domain-Specific Quality of Life in Cancer Patients Receiving Chemotherapy.Journal of clinical medicine · 2026Article
- Malnutrition in gastrointestinal cancer manifests before systemic therapy and is associated with fatigue and reduced physical quality of life.The oncologist · 2026Observational
- Electroencephalogram-guided anesthesia and postoperative anxiety and depression in elderly gastric cancer patients with sleep disorders.World journal of psychiatry · 2026Article
- Effects of Dietary Interventions on Nutritional Status in Patients with Gastrointestinal Cancers: A Systematic Review.Biomedicines · 2026Review
- Factors Associated with Nutritional Risk in Colorectal Cancer Patients Undergoing Chemotherapy: A Secondary Analysis of a Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2026Article
- One-year post-discharge health-related quality of life in digestive and oncology patients: a three-group comparison by nutritional status and care.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Caregiver-involved nutritional support and mindfulness training for patients with gastrointestinal cancer: Effects on malnutrition risk and mood.World journal of gastrointestinal oncology · 2025Article
- Foodservice interventions and their influence on nutritional outcomes and satisfaction of adult oncology patients-a conceptual replication.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Review
- Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study.Journal of cancer survivorship : research and practice · 2024Observational
- Article
- Article
- Pharmacomicrobiomics in precision cancer therapy: bench to bedside.Frontiers in immunology · 2024Review
- Effectiveness of the nutrition referral system in a multidisciplinary pancreatic cancer clinic.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Effect of Early Nutritional Support on Quality of Life by EORTC QLQ-C30 in Allogeneic Hematopoietic Stem Cell Transplantation.Blood cell therapy · 2022Article
- Supportive care interventions for cancer patients in low- and middle-income countries (LMICs): a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe best treatment therapy for gastrointestinal cancer patients is assessed by the improvement of health status and quality of life (QoL) after treatments. Malnutrition is related to loss of muscle strengths which leads to lower physical performance and emotional status. Thus, this study aimed to estimate the effects of nutritional interventions on the improvement of QoL among gastrointestinal patients undergoing chemotherapy in Vietnam.
methodsA quasi-experiment with intervention and control groups for pre- and post-intervention assessment was carried out at the Department of Oncology and Palliative Care-Hanoi Medical University Hospital from 2016 to 2019. Sixty gastrointestinal cancer patients were recruited in each group. The intervention regimen consisted of nutritional counseling, a specific menu with a recommended amount of energy, protein, and formula milk used within 2 months. Nutritional status and QoL of patients were evaluated using The Scored Patient-Generated Subjective Global Assessment (PG-SGA) and The European Organization for Research and Treatment of Cancer (EORTC). The difference in differences (DiD) method was utilized to estimate the outcome between control and intervention groups.
resultsAfter the intervention, patients of the intervention group had better changes in scores of global health status (Coef =16.68; 95% CI =7.90; 25.46), physical (Coef =14.51; 95% CI =5.34; 23.70), and role functioning (Coef =14.67; 95% CI =1.63; 27.70) compared to the control group. Regarding symptom scales, the level of fatigue, pain, and insomnia symptoms significantly reduced between pre- and post-intervention in the intervention group. In addition, living in urban areas, defined as malnourished and having low prealbumin levels, were positively associated with the lower global health status/QoL score.
conclusionNutritional therapy with high protein was beneficial to the improvement in QoL, physical function and the reduction of negative symptoms among gastrointestinal cancer patients. Early individualized nutritional support in consultation with professional dietitians during chemotherapy plays an integral part in enhancing the QoL and better treatment prognosis. CLINICAL TRIAL REGISTRATION NUMBER: NCT04517708.
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