ArticleAnnals of nuclear medicine2021
Digital PET/CT allows for shorter acquisition protocols or reduced radiopharmaceutical dose in [
Article in Annals of nuclear medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cumulative radiation doses due to nuclear medicine examinations: a systematic review.The British journal of radiology · 2021Pooled it
- Feasibility Study of Deep Learning-Driven Image Restoration for Fast, Low-Count [Diagnostics (Basel, Switzerland) · 2026Article
- Optimization of a Q.Clear PET image reconstruction based on bayesian optimization in oncology and neurology applications.Physical and engineering sciences in medicine · 2026Article
- An AI-Based Solution for Denoising Fast-Acquisition [Journal of imaging informatics in medicine · 2026Article
- Imaging of Small Lung Nodules on Modern SAFOV and LAFOV PET in Combination With Data-driven Motion Correction: Implications for Current Practice.Clinical nuclear medicine · 2026Article
- Digital versus analogue PET in parathyroid imaging: comparison of PET metrics and machine learning-based characterisation of hyperfunctioning lesions (the DIGI-PET study).European journal of nuclear medicine and molecular imaging · 2026Article
- Assessing small-lesion detectability and acquisition time optimisation in silicon-detector-Based PET: a phantom study.EJNMMI physics · 2025Article
- Lung lesion detectability on images obtained from decimated and CNN-based denoised [European journal of nuclear medicine and molecular imaging · 2025Article
- Lymphoma Therapy Response Assessment with Low-Dose [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Clinical Performance of Analog and Digital 18F-FDG PET/CT in Pediatric Epileptogenic Zone Localization: Preliminary Results.Biomedicines · 2025Article
- Diagnostic accuracy in NSCLC lymph node staging with Total-Body and conventional PET/CT.European journal of nuclear medicine and molecular imaging · 2025Article
- Time to shift to Digital PET/CT?Nuclear medicine and molecular imaging · 2025Article
- The impact of long axial field of view (LAFOV) PET on oncologic imaging.European journal of radiology · 2025Review
- Long-axial field-of-view PET/CT improves radiomics feature reliability.European journal of nuclear medicine and molecular imaging · 2025Article
- Automated Measurement of Effective Radiation Dose byTomography (Ann Arbor, Mich.) · 2024Article
- Long-Axial Field-of-View PET Imaging in Patients with Lymphoma: Challenges and Opportunities.PET clinics · 2024Review
- Dose Reduction in Pediatric Oncology Patients with Delayed Total-Body [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- Imaging Procedure and Clinical Studies of [Nuclear medicine and molecular imaging · 2024Review
- The clinical acceptability of short versus long duration acquisitions for head and neck cancer using long-axial field-of-view PET/CT: a retrospective evaluation.European journal of nuclear medicine and molecular imaging · 2024Article
- Technical NEMA NU2-2018 Performance Assessment of Time-of-Flight-Integrated Digital PET-CT System.World journal of nuclear medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo establish the feasibility of shorter acquisition times (and by analogy, applied activity) on tumour detection and lesion contrast in digital PET/CT.
methodsTwenty-one randomly selected patients who underwent oncological [
resultsOverall n = 100 lesions were identified in the 2 min and 1 min/bp acquisitions and n = 98 lesions in the 30 s/bp acquisitions. Agreement between the three acquisitions with respect to lesion number and tumour-to-background ratio showed almost perfect agreement (K's α = 0.999). SUVmax, SUVmean and TBR likewise showed > 98% agreement, with longer acquisitions being associated with slightly higher mean TBR (2 min/bp 7.94 ± 4.41 versus 30 s/bp 7.84 ± 4.22, p < 0.05).
conclusionShorter acquisition times have traditionally been associated with reduced lesion detectability or the requirement for larger amounts of radiotracer activity. These data confirm that this is not the case for new-generation digital PET scanners, where the known higher sensitivity results in clinically adequate images for shorter acquisitions. Only a small variation in the semi-quantitative parameters SUVmax, SUVmean and TBR was seen, confirming that either reduction of acquisition time or (by analogy) applied activity can be reduced as much as 75% in digital PET/CT without apparent clinical detriment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.