Evidence map›Paper›PMID 33550495›Full record

ArticleJournal of autism and developmental disorders2021

Rethinking Measurement Standards of Autism Symptomology in Adolescents with Fragile X Syndrome.

Heather Fielding-Gebhardt, Shelley L Bredin-Oja, Steven F Warren, Nancy C Brady

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Heather Fielding-GebhardtChild Language Doctoral Program, University of Kansas, 1000 Sunnyside Ave, Lawrence, KS, 66045, USA. fielding.h@ku.edu.ORCID http://orcid.org/0000-0003-4841-5208
Shelley L Bredin-OjaThe Life Span Institute, University of Kansas, Lawrence, KS, USA.
Steven F WarrenThe Life Span Institute, University of Kansas, Lawrence, KS, USA.
Nancy C BradyThe Life Span Institute, University of Kansas, Lawrence, KS, USA.

Funding

The Effects of Parenting on the Development and Behavior of Adolescents with FXSR01HD084563 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI NANCY CAROLINE BRADY · 2016 to 2026
$4.7M
TRAINING RESEARCHERS IN LANGUAGE IMPAIRMENTST32DC000052 · NIDCD · UNIVERSITY OF KANSAS LAWRENCE · PI RICE, MABEL L · 1995 to 2022
$2.7M
NICHD NIH HHS R01 HD084563NIDCD NIH HHS T32 DC000052
6 · The paper itself

Abstract

Accurate representation of autism spectrum disorder (ASD) in fragile X syndrome (FXS) is necessary for the field. We examined classifications of ASD using three approaches-Autism Diagnostic Observation Schedule (ADOS-2; Lord et al. 2012), Childhood Autism Rating Scale (CARS2-ST; Schopler et al. 2010), and Vineland Adaptive Behavior Scales (VABS-II; Sparrow et al. 2005)-in 45 adolescents with FXS. Maladaptive items from the VABS-II plus a maternal interview were matched with Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5; American Psychiatric Association 2013) criteria for ASD. Results indicated discrepant classifications. The ADOS-2 yielded the highest rate of comorbid autism (71%); CARS2-ST and VABS-II/DSM-5 yielded lower rates (38% and 42%, respectively). A singular measure of autism symptomology is insufficient to characterize autism in FXS.

Indexed as

Autism Spectrum DisorderAutistic DisorderFragile X SyndromeAdolescentChildDiagnostic and Statistical Manual of Mental DisordersHumansAutismFragile X syndromeMeasurement

Identifiers

PMID33550495
PMCPMC8342619

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.