Evidence map›Paper›PMID 33550453›Full record

ArticleLangenbeck's archives of surgery2021

Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany.

Arnulf G Willms, Karl J Oldhafer, Sophie Conze, Wolfgang E Thasler, Christian von Schassen, Thorsten Hauer, Tobias Huber, Christoph-Thomas Germer, Simone Günster, Dirk R Bulian and 13 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 14 institutions in 1 country.

Arnulf G WillmsKlinik für Allgemein- und Viszeralchirurgie, Thoraxchirurgie, Bundeswehrzentralkrankenhaus Koblenz, Koblenz, Germany. ArnulfWillms@bundeswehr.org.ORCID http://orcid.org/0000-0001-9998-6735
Karl J OldhaferKlinik für Leber-, Gallenwegs- und Pankreaschirurgie, Asklepios Klinik Barmbeck, Hamburg, Germany.
Sophie ConzeKlinik für Allgemein- und Viszeralchirurgie, Thoraxchirurgie, Bundeswehrzentralkrankenhaus Koblenz, Koblenz, Germany.
Wolfgang E ThaslerAbteilung für Allgemein-, Viszeral-, Thorax- und Minimalinvasive Chirurgie, Rot-Kreuz-Klinikum München, München, Germany.
Christian von SchassenKlinik für Allgemein- Viszeral- und Thoraxchirurgie, Bundeswehrkrankenhaus Hamburg, Hamburg, Germany.
Thorsten HauerKlinik für Allgemein-, Viszeral- und Thoraxchirurgie, Bundeswehrkrankenhaus Berlin, Berlin, Germany.
Tobias HuberKlinik für Allgemein-, Viszeral-und Transplantationschirurgie, Universitätsmedizin Mainz, Mainz, Germany.
Christoph-Thomas GermerKlinik und Poliklinik für Allgemein-, Viszeral-, Transplantations-, Gefäß- und Kinderchirurgie, Universitätsklinikum Würzburg, Würzburg, Germany.
Simone GünsterOperatives Zentrum für Allgemeinchirurgie, Klinikum Fürth, Fürth, Germany.
Dirk R BulianKlinik für Viszeral-, Tumor-, Transplantations- und Gefäßchirurgie, Kliniken der Stadt Köln, Standorte Merheim und Holweide, Köln, Germany.
Zarah HircheKlinik für Allgemein-, Viszeral- und Thoraxchirurgie, Klinikum Ludwigshafen am Rhein, Ludwigshafen, Germany.
Jörg FilserKlinik für Allgemein-, Viszeral- und Thoraxchirurgie, InnKlinikum Altötting und Mühldorf, Altötting, Germany.
Gregor A StavrouKlinik für Allgemein- und Viszeralchirurgie, Thoraxchirurgie, Chirurgische Onkologie, Klinikum Saarbrücken, Saarbrücken, Germany.
Martin ReichertKlinik für Allgemein-, Viszeral-, Thorax-, Transplantations- und Kinderchirurgie, Universitätsklinikum Gießen, Gießen, Germany.
Patrizia MalkomesKlinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Frankfurt, Frankfurt, Germany.
Steffen SeyfriedChirurgische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany.
Tobias LudwigAbteilung für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie, Universitätsmedizin Rostock, Rostock, Germany.
Hans C HillebrechtKlinik für Allgemein- und Viszeralchirurgie, Universitätsklinikum Freiburg, Freiburg, Germany.
Dimitrios PantelisAbteilung für Allgemein- und Viszeralchirurgie, GFO Kliniken Bonn, Bonn, Germany.
Stefanie BrunnerKlinik und Poliklinik für Allgemein-, Viszeral-, Tumor- und Transplantationschirurgie, Uniklinik Köln, Köln, Germany.
Wilm RostKlinik für Allgemein- Viszeral- und Thoraxchirurgie, Bundeswehrkrankenhaus Hamburg, Hamburg, Germany.
Johan F LockKlinik und Poliklinik für Allgemein-, Viszeral-, Transplantations-, Gefäß- und Kinderchirurgie, Universitätsklinikum Würzburg, Würzburg, Germany.
CAMIN Study Group
Universitäts-Kinderklinik Würzburg · DEAsklepios Klinik Barmbek · DEBundeswehrkrankenhaus · DEGoethe University Frankfurt · DEJohannes Gutenberg University Mainz · DEKliniken der Stadt Köln · DEKlinik und Poliklinik für Psychosomatik und Psychotherapie · DEUniversity Medical Center Freiburg · DEBundeswehrzentralkrankenhaus Koblenz · DEHeidelberg University · DEKlinikum Ludwigshafen · DEKlinikum Saarbrücken · DERotkreuzklinikum München · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe COVID-19 pandemic has transformed medical care worldwide. General surgery has been affected in elective procedures, yet the implications for emergency surgery are unclear. The current study analyzes the effect of the COVID-19 lockdown in spring 2020 on appendicitis treatment in Germany.

methodsHospitals that provided emergency surgical care during the COVID-19 lockdown were invited to participate. All patients diagnosed with appendicitis during the lockdown period (10 weeks) and, as a comparison group, patients from the same period in 2019 were analyzed. Clinical and laboratory parameters, intraoperative and pathological findings, and postoperative outcomes were analyzed.

resultsA total of 1915 appendectomies from 41 surgical departments in Germany were included. Compared to 2019 the number of appendectomies decreased by 13.5% (1.027 to 888, p=0.003) during the first 2020 COVID-19 lockdown. The delay between the onset of symptoms and medical consultation was substantially longer in the COVID-19 risk group and for the elderly. The rate of complicated appendicitis increased (58.2 to 64.4%), while the absolute number of complicated appendicitis decreased from 597 to 569, (p=0.012). The rate of negative appendectomies decreased significantly (6.7 to 4.6%; p=0.012). Overall postoperative morbidity and mortality, however, did not change.

conclusionThe COVID-19 lockdown had significant effects on abdominal emergency surgery in Germany. These seem to result from a stricter selection and a longer waiting time between the onset of symptoms and medical consultation for risk patients. However, the standard of emergency surgical care in Germany was maintained.

Indexed as

Communicable Disease ControlAdolescentAdultAgedAppendectomyAppendicitisCOVID-19FemaleGermanyHumansLength of StayMaleMiddle AgedPostoperative ComplicationsProcedures and Techniques UtilizationRetrospective StudiesAppendicitisComplicated appendicitisCOVID-19Emergency surgeryMulticenter studySARS-CoV-2

Identifiers

PMID33550453
PMCPMC7867500
OpenAlexW3129031105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.