ArticleMedical science monitor : international medical journal of experimental and clinical research2021
Comparative Analysis of 3D-Printed Artificial Vertebral Body Versus Titanium Mesh Cage in Repairing Bone Defects Following Single-Level Anterior Cervical Corpectomy and Fusion.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05396222 (A Prospective Study of the Safety and Efficacy of 3D-printed Custom-made Non-rigid Biomimetic Implant for Anterior Column Reconstruction in Cervical and Thoracolumbar Spine), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Study of the Safety and Efficacy of 3D-printed Custom-made Non-rigid Biomimetic Implant for Anterior Column Reconstruction in Cervical and Thoracolumbar Spine
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Risk factors for cage subsidence in patients undergoing cervical fusion: a systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Comparison of clinical efficacy of 3D-printed artificial vertebral body and conventional titanium mesh cage in spinal reconstruction after total en bloc spondylectomy for spinal tumors: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Self-stabilizing zero-profile 3D-printed vertebral body versus traditional titanium mesh-cage with plate in anterior cervical corpectomy and fusion: an open-label randomized controlled trial on efficacy and complications for cervical spondylotic myelopathy.Journal of orthopaedic surgery and research · 2026Trial
- Three-dimensional printed artificial vertebral body versus titanium mesh cage and nanohydroxyapatite/polyamide-66 cage in anterior cervical corpectomy and fusion: a retrospective cohort study with a minimum 5-year follow-up.Journal of orthopaedic surgery and research · 2026Observational
- Review
- Preoperative imaging predictors of subsidence of 3D-printed artificial cervical vertebral bodies: a cohort study of 102 patients with nomogram development and validation.BMC musculoskeletal disorders · 2026Article
- Structural design and biomechanical analysis of anti- subsidence gradient porous artificial vertebrae combined with a topology framework.BMC musculoskeletal disorders · 2026Article
- Combined flap with Masquelet technique and 3D-printed titanium cage for reconstruction of traumatic composite heel defects: a case report and literature review.Frontiers in surgery · 2026Article
- Artificial vertebral body versus titanium mesh cage for single-level anterior cervical corpectomy and fusion (ACCF): a propensity score matching analysis of fusion, implant subsidence and clinical outcomes.BMC musculoskeletal disorders · 2025Article
- Transforming spinal surgery with innovations in biologics and additive manufacturing.Materials today. Bio · 2025Review
- The rational design, biofunctionalization and biological properties of orthopedic porous titanium implants: a review.Frontiers in bioengineering and biotechnology · 2025Review
- Using additive manufacturing for craniocervical reconstruction in traditionally challenging cases.Neurosurgical review · 2024Article
- Clinical Application of 3D-Printed Artificial Vertebral Body (3DP AVB): A Review.Journal of personalized medicine · 2024Review
- Application of 3D‑printed porous titanium interbody fusion cage vs. polyether ether ketone interbody fusion cage in anterior cervical discectomy and fusion: A systematic review and meta‑analysis update.Experimental and therapeutic medicine · 2024Article
- [Treatment of cervical ossification of posterior longitudinal ligament with titanium alloy trabecular bone three-dimensional printed artificial vertebral body].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Article
- [Application of self-stabilizing zero-profile three-dimensional printed artificial vertebral bodies for treatment of cervical spondylotic myelopathy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024Article
- Cervical spine reconstruction after total vertebrectomy using customized three-dimensional-printed implants in dogs.Journal of veterinary science · 2024Article
- Surgical outcomes and risk factors for surgical complications after en bloc resection following reconstruction with 3D-printed artificial vertebral body for thoracolumbar tumors.World journal of surgical oncology · 2023Article
- A novel artificial vertebral implant with Gyroid porous structures for reducing the subsidence and mechanical failure rate after vertebral body replacement.Journal of orthopaedic surgery and research · 2023Article
- Implant failure and revision strategies after total spondylectomy for spinal tumors.Journal of bone oncology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The aim of this study was to compare the clinical and radiological outcomes of the 3D-printed artificial vertebral body vs the titanium mesh cage in repairing bone defects for single-level anterior cervical corpectomy and fusion (ACCF). MATERIAL AND METHODS A total of 51 consecutive patients who underwent single-level ACCF in Huai'an Second People's Hospital from July 2017 to August 2020 were retrospectively reviewed. According to the implant materials used, patients were divided into a 3D-printed artificial vertebral body group (3D-printed group) (n=20; 12 males, 8 females) and a titanium mesh cage group (TMC group) (n=31; 15 males, 16 females). General data, radiological parameters, and clinical outcomes were recorded. RESULTS The rate of subsidence in the 3D-printed group (0.01, 2/20) was lower than in the TMC group (0.29, 9/31) (P<0.05). HAE and HPE of the patients in the 3D-printed group were significantly higher than those in the TMC group (P<0.05). C2-C7 Cobb angle and SA of the patients in the 3D-printed group were significantly larger than those in the TMC group (P<0.05). All patients in the 2 groups showed significant improvement in VAS, JOA, and NDI scores at 3 months and 1 year after surgery. CONCLUSIONS 3D-printed artificial vertebral body helps maintain intervertebral height and cervical physiological curvature and is a good candidate for ACCF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.