Evidence map›Paper›PMID 33550225›Full record

ArticleBMJ open2021

Retrospective cohort study to investigate the 10-year trajectories of disease patterns in patients with hypertension and/or diabetes mellitus on subsequent cardiovascular outcomes and health service utilisation: a study protocol.

Eric Yuk Fai Wan, Weng Yee Chin, Esther Yee Tak Yu, Julie Chen, Emily Tsui Yee Tse, Carlos King Ho Wong, Tony King Hang Ha, David Vai Kiong Chao, Wendy Wing Sze Tsui, Cindy Lo Kuen Lam

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04302974 (Cohort Study to Investigate the Outcomes of Patients With Hypertension and/or Diabetes Mellitus and the Effectiveness and Cost-effectiveness of Structured Multi-disciplinary Intervention Programmes), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04302974 completednot on this map

Cohort Study to Investigate the Outcomes of Patients With Hypertension and/or Diabetes Mellitus and the Effectiveness and Cost-effectiveness of Structured Multi-disciplinary Intervention Programmes

TypeobservationalSponsorThe University of Hong KongRan2019 to 2024Enrolled100,000ConditionsHypertension, Diabetes Mellitus, Cardiovascular Diseases, Morbidity, MultipleArmsDifferent structures and processes of primary care management strategies, Multi-disciplinary Risk Factor Assessment and Management Programmes for diabetes (RAMP-DM), Multi-disciplinary Risk Factor Assessment and Management Programmes for hypertension (RAMP-HT), Patient Support Call Centre (PSCC)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Eric Yuk Fai WanDepartment of Family Medicine and Primary Care, University of Hong Kong, Hong Kong, China yfwan@hku.hk.ORCID 0000-0002-6275-1147
Weng Yee ChinDepartment of Family Medicine and Primary Care, University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3171-6792
Esther Yee Tak YuDepartment of Family Medicine and Primary Care, University of Hong Kong, Hong Kong, China.ORCID 0000-0001-7472-7083
Julie ChenDepartment of Family Medicine and Primary Care, University of Hong Kong, Hong Kong, China.
Emily Tsui Yee TseDepartment of Family Medicine and Primary Care, University of Hong Kong, Hong Kong, China.
Carlos King Ho WongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong Island, China.ORCID 0000-0002-6895-6071
Tony King Hang HaPrimary and Community Services, Hospital Authority, Hong Kong, China.
David Vai Kiong ChaoDepartment of Family Medicine and Primary Health Care, Hospital Authority Kowloon East Cluster, Kowloon, China.
Wendy Wing Sze TsuiFamily Medicine & Primary Healthcare, Hospital Authority Hong Kong West Cluster, Hong Kong Island, China.
Cindy Lo Kuen LamDepartment of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong SAR, China.
University of Hong Kong · HKHospital Authority · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension (HT) and diabetes mellitus (DM) and are major disease burdens in all healthcare systems. Given their high impact on morbidity, premature death and direct medical costs, we need to optimise effectiveness and cost-effectiveness of primary care for patients with HT/DM. This study aims to find out the association of trajectories in disease patterns and treatment of patients with HT/DM including multimorbidity and continuity of care with disease outcomes and service utilisation over 10 years in order to identify better approaches to delivering primary care services. METHODS AND ANALYSIS: A 10-year retrospective cohort study on a population-based primary care cohort of Chinese patients with documented doctor-diagnosed HT and/or DM, managed in the Hong Kong Hospital Authority (HA) public primary care clinics from 1 January 2006 to 31 December 2019. Data will be extracted from the HA Clinical Management System to identify trajectory patterns of patients with HT/DM. Complications defined by ICPC-2/International Classification of Diseases-Ninth Revision, Clinical Modification diagnosis codes, all-cause mortality rates and public service utilisation rates are included as independent variables. Changes in clinical parameters will be investigated using a growth mixture modelling analysis with standard quadratic trajectories. Dependent variables including effects of multimorbidity, measured by (1) disease count and (2) Charlson's Comorbidity Index, and continuity of care, measured by the Usual Provide Continuity Index, on patient outcomes and health service utilisation will be investigated. Multivariable Cox proportional hazards regression will be conducted to estimate the effect of multimorbidity and continuity of care after stratification of patients into groups according to respective definitions. ETHICS AND DISSEMINATION: This study was approved by the institutional review board of the University of Hong Kong-the HA Hong Kong West Cluster, reference no: UW 19-329. The study findings will be disseminated through peer-reviewed publications and international conferences. TRIAL REGISTRATION NUMBER: NCT04302974.

Indexed as

Diabetes MellitusHypertensionCohort StudiesHealth ServicesHong KongHumansRetrospective Studiesgeneral diabeteshypertensionprimary carequality in health care

Identifiers

PMID33550225
PMCPMC7925871
OpenAlexW3127233879

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.