ArticleMolecular metabolism2021
Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography.
Article in Molecular metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Image Quality Improvement Techniques and Assessment Adequacy in Clinical Optoacoustic Imaging: A Systematic Review.Biosensors · 2022Pooled it
- Optoacoustic muscle imaging.Journal of neuromuscular diseases · 2026Review
- Differentiation of sphingomyelin and cholesterol by hyperspectral mid-infrared detection of single-bond vibrational modes in the fingerprint region.Nature methods · 2026Article
- Mapping glucose-induced hemodynamics in white fat depots with label-free optoacoustics.Photoacoustics · 2026Article
- Motion score for spectral quality control of optoacoustic-ultrasound data.Scientific reports · 2026Article
- A primer on current status and future opportunities of clinical optoacoustic imaging.Npj imaging · 2025Review
- Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults.Photoacoustics · 2024Article
- Clinical and Translational Imaging and Sensing of Diabetic Microangiopathy: A Narrative Review.Journal of cardiovascular development and disease · 2023Review
- Skeletal muscle optoacoustics reveals patterns of circulatory function and oxygen metabolism during exercise.Photoacoustics · 2023Article
- Non-invasive multispectral optoacoustic tomography resolves intrahepatic lipids in patients with hepatic steatosis.Photoacoustics · 2023Article
- Optoacoustic biomarkers of lipids, hemorrhage and inflammation in carotid atherosclerosis.Frontiers in cardiovascular medicine · 2023Review
- Multi-Aspect Optoacoustic Imaging of Breast Tumors under Chemotherapy with Exogenous and Endogenous Contrasts: Focus on Apoptosis and Hypoxia.Biomedicines · 2021Article
- Multispectral optoacoustic tomography of lipid and hemoglobin contrast in human carotid atherosclerosis.Photoacoustics · 2021Article
- Optoacoustic imaging in endocrinology and metabolism.Nature reviews. Endocrinology · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePostprandial lipid profiling (PLP), a risk indicator of cardiometabolic disease, is based on frequent blood sampling over several hours after a meal, an approach that is invasive and inconvenient. Non-invasive PLP may offer an alternative for disseminated human monitoring. Herein, we investigate the use of clinical multispectral optoacoustic tomography (MSOT) for non-invasive, label-free PLP via direct lipid-sensing in human vasculature and soft tissues.
methodsFour (n = 4) subjects (3 females and 1 male, age: 28 ± 7 years) were enrolled in the current pilot study. We longitudinally measured the lipid signals in arteries, veins, skeletal muscles, and adipose tissues of all participants at 30-min intervals for 6 h after the oral consumption of a high-fat meal.
resultsOptoacoustic lipid-signal analysis showed on average a 63.4% intra-arterial increase at ~ 4 h postprandially, an 83.9% intra-venous increase at ~ 3 h, a 120.8% intra-muscular increase at ~ 3 h, and a 32.8% subcutaneous fat increase at ~ 4 h.
conclusionMSOT provides the potential to study lipid metabolism that could lead to novel diagnostics and prevention strategies by label-free, non-invasive detection of tissue biomarkers implicated in cardiometabolic diseases.
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