Evidence map›Paper›PMID 33549621›Full record

ArticleEnvironmental research2021

Household low pile carpet usage was associated with increased serum PFAS concentrations in 2005-2006.

Yachen Zhu, Annie Ro, Scott M Bartell

Abstract read
In one paragraph

Article in Environmental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yachen ZhuProgram in Public Health, University of California, Irvine, CA, 92697-3957, USA.
Annie RoProgram in Public Health, University of California, Irvine, CA, 92697-3957, USA.
Scott M BartellProgram in Public Health, University of California, Irvine, CA, 92697-3957, USA; Department of Environmental and Occupational Health, University of California, Irvine, CA, 92697-1250, USA; Department of Statistics, University of California, Irvine, CA, 92697-1250, USA. Electronic address: sbartell@uci.edu.

Funding

UCI PFAS Health StudyU01TS000308 · TS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARTELL, SCOTT MICHAEL, DETWILER, RUSSELL · 2019 to 2023
$6.9M
ATSDR CDC HHS U01 TS000308
6 · The paper itself

Abstract

backgroundPer- and polyfluoroalkyl substances (PFAS) are ubiquitous in the serum of the general US population. Food, drinking water, consumer products, dust, and air have been assessed as PFAS exposure sources for humans. The effects of various types of carpeting on serum PFAS concentrations have been less studied, despite the known use of PFAS in stain-resistant carpet treatments.

objectiveThis study aimed to examine the associations between serum PFAS concentrations and type of residential flooring among the general US population aged 12 years and older using the 2005-2006 National Health and Nutrition Examination Survey (NHANES).

methodsWe used multiple linear regressions adjusted for complex survey design and relevant covariates to analyze the relations between serum PFAS concentrations and type of floor covering (smooth surface, low pile carpet, medium to high pile carpet, and combination of carpet and smooth surface), as well as other potential exposure factors. We used multiple imputation to address missing values.

resultsWe found significantly higher serum concentrations of perfluorohexane sulfonic acid (PFHxS) and 2-(N-methyl-perfluorooctane sulfonamido) acetic acid (MeFOSAA) in US residents residing in homes with low pile carpeting compared with those residing in homes with smooth surface. We concluded that among US residents aged 12 years and older residing in homes with low pile carpeting in the home in 2005-2006, on average 24% and 19% of the PFHxS and MeFOSAA body burdens, respectively, could be attributed to carpeting. We found associations between other types of floor covering (medium to high pile carpet, combination of carpet and smooth surface) and some PFAS concentrations compared with the smooth surface, but these results were less consistent and generally not statistically significant. Additionally, a group Wald Chi-squared test showed a significant result for PFOS, indicating different contributions of various types of flooring to PFOS serum concentration. SIGNIFICANCE: Our results are representative of the general US population at the time of the survey, and potentially informative regarding ongoing PFAS exposure from a variety of sources including carpeting.

Indexed as

Alkanesulfonic AcidsEnvironmental PollutantsFluorocarbonsCaprylatesChildFloors and FloorcoveringsHumansNutrition SurveysSulfonic AcidsAlkanesulfonic AcidsCaprylatesEnvironmental PollutantsFluorocarbonsSulfonic AcidsCarpetingPFAS exposureSampling surveySerum

Identifiers

PMID33549621
PMCPMC8104467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.