Evidence map›Paper›PMID 33549332›Full record

ArticleTrends in neurosciences2021

Peptides, Breathing, and Sudden Infant Death Syndrome.

Nicholas J Burgraff, Nathan A Baertsch, Jan-Marino Ramirez

Open access · greenAbstract readComment
In one paragraph

Article in Trends in neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicholas J BurgraffCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA. Electronic address: nicholas.burgraff@seattlechildrens.org.
Nathan A BaertschCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Jan-Marino RamirezCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.
University of Washington · USCenter for Infectious Disease Research · US

Funding

Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4M
Unraveling respiratory rhythm generation in the medullary networkR01HL126523 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI Jan M. Ramirez · 2015 to 2026
$8.3M
Unraveling the dynamic mechanisms underlying opioid respiratory depressionR01HL144801 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI Jan M. Ramirez · 2019 to 2026
$5.2M
Neuroglial interactions underlying the generation of the sighR01HL151389 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI RAMIREZ, JAN M. · 2020 to 2023
$3.2M
Homeostatic Plasticity of the Respiratory Rhythm Generating NetworkR00HL145004 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI BAERTSCH, NATHAN ANDREW · 2021 to 2023
$747k
Homeostatic Plasticity of the Respiratory Rhythm Generating NetworkK99HL145004 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI BAERTSCH, NATHAN ANDREW · 2019 to 2020
$209k
Rhythmogenic states of the respiratory network reveal differential opioid sensitivityF32HL154558 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI BURGRAFF, NICHOLAS J · 2020 to 2023
$204k
NHLBI NIH HHS F32 HL154558NHLBI NIH HHS K99 HL145004NHLBI NIH HHS P01 HL090554NHLBI NIH HHS R00 HL145004NHLBI NIH HHS R01 HL126523NHLBI NIH HHS R01 HL144801NHLBI NIH HHS R01 HL151389
6 · The paper itself

Abstract

Shi et al. recently identified a brainstem peptidergic circuit in mice that is activated at birth and stabilizes breathing during the transition from the intra-utero environment to air breathing. This network remains important for maintaining stable breathing and respiratory homeostasis throughout development, and deficiencies in this network may be linked to sudden infant death syndrome (SIDS).

Indexed as

Sudden Infant DeathAnimalsBrain StemMicePeptidesRespirationPeptidesbreathingPACAPpreBötzinger complexRTN

Identifiers

PMID33549332
PMCPMC8645383
OpenAlexW3127218385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.