ArticleBMC neurology2021
Effectiveness of mechanical thrombectomy in cancer-related stroke and associated factors with unfavorable outcome.
Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025).Journal of evidence-based medicine · 2026Guideline
- Impact of D-dimer on the outcomes of endovascular thrombectomy for acute ischemic stroke: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Pooled it
- The Thrombectomy Dilemma in Stroke Patients With Active Cancer: To Treat or Not to Treat?Journal of stroke · 2026Review
- Concurrent Use of Contact Aspiration and a Stent Retriever Is Associated With Successful Recanalization in Patients With Cancer-Associated Stroke.Journal of clinical neurology (Seoul, Korea) · 2026Article
- Outcomes of patients with in-hospital stroke with and without active cancer.Journal of thrombosis and thrombolysis · 2025Article
- Endovascular recanalization of symptomatic chronic cerebral artery occlusion: predictors for successful recanalization and perioperative complications.Frontiers in neurology · 2025Article
- Usefulness of Mechanical Thrombectomy in Patients with Cancer Who Developed Cerebral Infarction.Neurologia medico-chirurgica · 2024Article
- Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke in Cancer Patients: A Single-Center Experience and Meta-Analysis.Neurology. Clinical practice · 2024Article
- Long-term outcomes of mechanical thrombectomy in acute ischaemic stroke patients with concomitant malignancy.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- A Single-Center Experience of Mechanical Thrombectomy for Cancer-Associated Ischemic Stroke.Journal of neuroendovascular therapy · 2024Article
- Preprocedural D-Dimer Level as a Predictor of First-Pass Recanalization and Functional Outcome in Endovascular Treatment of Acute Ischemic Stroke.Journal of clinical medicine · 2023Article
- Factors related to white thrombi in acute ischemic stroke in cancer patients.The neuroradiology journal · 2023Article
- Does Malignancy Status Effect Outcomes in Patients With Large Vessel Occlusion Stroke and Cancer Who Underwent Endovascular Thrombectomy?Journal of the American Heart Association · 2023Article
- Article
- Endovascular Treatment in Patients With Acute Ischemic Stroke and Comorbid Cancer: Analysis of the Italian Registry of Endovascular Treatment in Acute Stroke.Stroke (Hoboken, N.J.) · 2023Article
- Cancer-Associated Stroke and Acute Endovascular Reperfusion Therapy.Journal of neuroendovascular therapy · 2023Review
- Acute reperfusion treatment and secondary prevention of cancer-related stroke: comprehensive overview and proposal of clinical algorithm.Therapeutic advances in neurological disorders · 2023Review
- Treatment of acute ischemic stroke in patients with active malignancy: insight from a comprehensive stroke center.Therapeutic advances in neurological disorders · 2023Article
- Mechanical Thrombectomy for Acute Ischemic Stroke in Metastatic Cancer Patients: A Nationwide Cross-Sectional Analysis.Journal of stroke · 2023Article
- Endovascular treatment in patients with acute ischemic stroke and cancer: Systematic review and meta-analysis.European stroke journal · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effectiveness of mechanical thrombectomy (MT) in cancer-related stroke (CRS) is largely unknown. This study aims to investigate the clinical and radiological outcomes of MT in CRS patients. We also explored the factors that independently affect functional outcomes of patients with CRS after MT.
methodsWe retrospectively reviewed 341 patients who underwent MT after acute ischemic stroke onset between May 2014 and May 2020. We classified the patients into CRS (n = 34) and control (n = 307) groups and compared their clinical details. Among CRS patients, we analyzed the groups with and without good outcomes (3-months modified Rankin scale [mRS] score 0, 1, 2). Multivariate analysis was performed to investigate the independent predictors of unfavorable outcomes in patients with CRS after MT.
resultsA total of 341 acute ischemic stroke patients received MT, of whom 34 (9.9%) had CRS. Although the baseline National institute of health stroke scale (NIHSS) score and the rate of successful recanalization was not significantly different between CRS patients and control group, CRS patients showed more any cerebral hemorrhage after MT (41.2% vs. controls 23.8%, p = 0.037) and unfavorable functional outcome at 3 months (CRS patients median 3-month mRS score 4, interquartile range [IQR] 2 to 5.25 vs. controls median 3-month mRS score 3, IQR 1 to 4, [p = 0.026]). In the patients with CRS, elevated serum D-dimer level and higher baseline NIHSS score were independently associated with unfavorable functional outcome at 3 months (adjusted odds ratio [aOR]: 1.524, 95% confidence interval [CI]: 1.043-2.226; aOR: 1.264, 95% CI: 1.010-1.582, respectively).
conclusionsMT is an appropriate therapeutic treatment for revascularization in CRS patients. However, elevated serum D-dimer levels and higher baseline NIHSS scores were independent predictors of unfavorable outcome. Further research is warranted to evaluate the significance of these predictors.
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